In humans, the combination of all sex-specific genetic, epigenetic, and hormonal influences
of biologic sex produces different in vivo environments for male and female cells. We dissect …

Cardiovascular disease is the leading cause of death in women and men globally, with most
due to atherosclerotic cardiovascular disease (ASCVD). Despite progress during the last 30 …

An initiation-promotion protocol was used to test the hypothesis that unleaded gasoline (UG)
vapor acts as a liver tumor promoter in female mice under exposure conditions in which UG …

Ischaemic heart disease (IHD) is the leading cause of death in women as in men, although
presentation in women is on average 7–10 years later. Recent temporal trends show …

Cardiovascular diseases (CVD) have a lower prevalence in women than men; although, a
higher mortality rate and a poorer prognosis are more common in women. However, there is …

Antiplatelet therapy is a cornerstone of secondary prevention of cardiovascular diseases
(CVDs). However, current guidelines are based on data derived primarily from men, as …

Transcatheter aortic valve replacement (TAVR) has gained over time a major reduction in
procedural complications. Despite this, clinically relevant bleeding still occurs in a non …

Background Gender influences platelet biology. Women have a larger platelet count, but
gender-based differences in platelet function remain debated. We performed a study …

The is growing awareness that the underrepresentation of women in clinical trials and in
particular in phase I studies may lead to incorrect handling of drugs. Despite the fact that …

In patients with atrial fibrillation (AF), the safety and efficacy of nonvitamin K antagonist oral
anticoagulants (NOACs) vs warfarin according to diabetes mellitus (DM) status are not …