The genetic diversity of Trypanosoma cruzi, the protozoan agent of Chagas disease, is
widely recognized. At present, T. cruzi is partitioned into seven discrete typing units (DTUs) …

The protozoan Trypanosoma cruzi, its mammalian reservoirs, and vectors have existed in
nature for millions of years. The human infection, named Chagas disease, is a major public …

Chagas disease is a chronic, systemic, parasitic infection caused by the protozoan
Trypanosoma cruzi, and was discovered in 1909. The disease affects about 8 million people …

Over the last 30 years, concomitant with successful transnational disease control programs
across Latin America, Chagas disease has expanded from a neglected, endemic parasitic …

Chagas disease, or American trypanosomiasis, is the result of infection by the parasite
Trypanosoma cruzi. It is endemic in Latin America, and spreading around the globe due to …

Intracellular parasitism has arisen only a few times during the long ancestry of protozoan
parasites including in diverse groups such as microsporidians, kinetoplastids, and …

Acquisition of detailed knowledge of the structure and evolution of Trypanosoma cruzi
populations is essential for control of Chagas disease. We profiled 75 strains of the parasite …

Chagas disease, caused by the infection with T rypanosoma cruzi, is endemic in all L atin A
merica. Due to the increase in population migration, C hagas disease has spread worldwide …

Genetic variation in Trypanosoma cruzi is likely a key determinant in transmission and
pathogenesis of Chagas disease. We have examined nine loci as markers for the extant T …

Background. One hundred years after the discovery of Chagas disease, it remains a major
neglected tropical disease. Chronic Chagas heart disease (cChHD) is the most severe …