Foam cells play a vital role in the initiation and development of atherosclerosis. This review
aims to summarize the novel insights into the origins, consequences, and molecular …

Vascular smooth muscle cells (VSMCs) are involved in phenotypic switching in
atherosclerosis. This switching is characterized by VSMC dedifferentiation, migration, and …

Alterations in the vascular smooth muscle cells (VSMC) phenotype play a critical role in the
pathogenesis of several cardiovascular diseases, including hypertension, atherosclerosis …

Over the last decades, life expectancy has significantly increased although several chronic
diseases persist in the population, with aging as the leading risk factor. Despite …

Atherosclerosis is a chronic and progressive process. It is the most important pathological
basis of cardiovascular disease and stroke. Vascular smooth muscle cells (VSMCs) are an …

The dramatic increase in global prevalence of metabolic disease is inexplicable when
considering only environmental or only genetic factors, leading to the need to explore the …

Atherosclerosis, characterized by the formation of fat-laden plaques, is a chronic
inflammatory disease. ABCA1 promotes cholesterol efflux, reduces cellular cholesterol …

Objective: Stress granules (SGs) are dynamic cytoplasmic aggregates containing mRNA,
RNA-binding proteins, and translation factors that form in response to cellular stress. SGs …

Cardiovascular diseases (CVDs) caused by arteriosclerosis are the leading cause of death
and disability worldwide. In the late stages of atherosclerosis, the atherosclerotic plaque …

The inflammatory response is a complex, tightly regulated process activated by tissue
wounding, foreign body invasion, and sterile inflammation. Over the decades, great progress …