Modern humanity wades daily through various radiations, resulting in frequent exposure and
causing potentially important biological effects. Among them, the brain is the organ most …

Reactive oxygen species (ROS) are produced as a result of aerobic metabolism and as by‐
products through numerous physiological and biochemical processes. While ROS …

Positive associations between external radiation dose and non-cancer mortality have been
found in a number of published studies, primarily of populations exposed to high-dose, high …

Radiation-induced brain injury (RIBI) after radiotherapy has become an increasingly
important factor affecting the prognosis of patients with head and neck tumor. With the …

The first phase of molecular brain imaging of microglial activation in neuroinflammatory
conditions began some 20 years ago with the introduction of [11C]-(R)-PK11195, the …

Microglia, the innate immune cells of the central nervous system, play a pivotal role in the
modulation of neuroinflammation. Neuroinflammation has been implicated in many diseases …

Population aging is occurring rapidly worldwide, challenging the global economy and
healthcare services. Brain aging is a significant contributor to various age-related …

Ionizing radiation (IR) is a high-energy radiation whose biological effects depend on the
irradiation doses. Low-dose radiation (LDR) is delivered during medical diagnoses or by an …

Glioblastoma multiforme (GBM) is the most malignant form of brain tumors, with a dismal
prognosis. During the course of the disease, microglia and macrophages both infiltrate the …

In a search for new antioxidants, a set of new iodoquinazolinone derivatives bearing
benzenesulfonamide moiety and variable acetamide pharmacophores 5–17 were designed …