SARS-COV-2 variants: differences and potential of immune evasion

SM Hirabara, TDA Serdan, R Gorjao… - Frontiers in cellular …, 2022 - frontiersin.org
The structural spike (S) glycoprotein of severe acute respiratory syndrome coronavirus-2
(SARS-CoV-2) plays an essential role in infection and is an important target for neutralizing …

The extracellular matrix as a multitasking player in disease

AD Theocharis, D Manou, NK Karamanos - The FEBS journal, 2019 - Wiley Online Library
Extracellular matrices (ECM s) are highly specialized and dynamic three‐dimensional (3D)
scaffolds into which cells reside in tissues. ECM is composed of a variety of fibrillar …

Extracellular matrix structure

AD Theocharis, SS Skandalis, C Gialeli… - Advanced drug delivery …, 2016 - Elsevier
Extracellular matrix (ECM) is a non-cellular three-dimensional macromolecular network
composed of collagens, proteoglycans/glycosaminoglycans, elastin, fibronectin, laminins …

The mammary gland: basic structure and molecular signaling during development

SK Biswas, S Banerjee, GW Baker, CY Kuo… - International Journal of …, 2022 - mdpi.com
The mammary gland is a compound, branched tubuloalveolar structure and a major
characteristic of mammals. The mammary gland has evolved from epidermal apocrine …

[HTML][HTML] Proteoglycan form and function: A comprehensive nomenclature of proteoglycans

RV Iozzo, L Schaefer - Matrix biology, 2015 - Elsevier
We provide a comprehensive classification of the proteoglycan gene families and respective
protein cores. This updated nomenclature is based on three criteria: Cellular and subcellular …

[HTML][HTML] Bone composition: relationship to bone fragility and antiosteoporotic drug effects

AL Boskey - BoneKEy reports, 2013 - ncbi.nlm.nih.gov
The composition of a bone can be described in terms of the mineral phase, hydroxyapatite,
the organic phase, which consists of collagen type I, noncollagenous proteins, other …

Short and tall stature: a new paradigm emerges

J Baron, L Sävendahl, F De Luca, A Dauber… - Nature Reviews …, 2015 - nature.com
In the past, the growth hormone (GH)–insulin-like growth factor 1 (IGF-1) axis was often
considered to be the main system that regulated childhood growth and, therefore …

Vascular extracellular matrix and arterial mechanics

JE Wagenseil, RP Mecham - Physiological reviews, 2009 - journals.physiology.org
An important factor in the transition from an open to a closed circulatory system was a
change in vessel wall structure and composition that enabled the large arteries to store and …

[HTML][HTML] SLAM family receptors distinguish hematopoietic stem and progenitor cells and reveal endothelial niches for stem cells

MJ Kiel, ÖH Yilmaz, T Iwashita, OH Yilmaz, C Terhorst… - cell, 2005 - cell.com
To improve our ability to identify hematopoietic stem cells (HSCs) and their localization in
vivo, we compared the gene expression profiles of highly purified HSCs and non-self …

Bone remodeling

DJ Hadjidakis, II Androulakis - Annals of the New York academy …, 2006 - Wiley Online Library
The skeleton is a metabolically active organ that undergoes continuous remodeling
throughout life. Bone remodeling involves the removal of mineralized bone by osteoclasts …