Triple-negative breast cancer (TNBC) is a subtype of breast cancer that is highly aggressive
and hypoxic compared with other subtypes. The role of hypoxia inducible factor 1α (HIF-1α) …

Simple Summary Factors such as estrogen, progesterone, and androgen receptors, also
known as nuclear receptors, are abundantly expressed in the majority of breast cancers …

The p38 MAPK is a signaling pathway important for cells to respond to environmental and
intracellular stress. Upon activation, the p38 kinase phosphorylates downstream effectors …

The most widespread, malignant, and deadliest type of glial tumor is glioblastoma
multiforme (GBM). Despite radiation, chemotherapy, and radical surgery, the median …

BACKGROUND Breast cancer is a common malignant tumor that seriously threatens
women's health. Breast cancer stem cell (CSC)-like cell population may be the main factor …

Breast cancer (BC) is one of the most common cancers in women worldwide. Even though
the role of estrogen receptor alpha (ERα) is extensively documented in the development of …

Triple-negative breast cancer (TNBC) has a poor clinical outcome, due to a lack of
actionable therapeutic targets. Herein we define lysosomal acid lipase A (LIPA) as a viable …

Corticosteroids act on the glucocorticoid receptor (GR; NR3C1) to resolve inflammation and
are routinely prescribed to breast cancer patients undergoing chemotherapy treatment to …

Purpose: Although high glucocorticoid receptor (GR) expression in early-stage estrogen
receptor (ER)-negative breast cancer is associated with shortened relapse-free survival …

Abstract Glucocorticoids (GCs), mostly dexamethasone (dex), are routinely administered as
adjuvant therapy to manage side effects in breast cancer. However, recently, it has been …