Cardiac progenitor cells from stem cells: learning from genetics and biomaterials

S Barreto, L Hamel, T Schiatti, Y Yang, V George - Cells, 2019 - mdpi.com
Cardiac Progenitor Cells (CPCs) show great potential as a cell resource for restoring cardiac
function in patients affected by heart disease or heart failure. CPCs are proliferative and …

Human PSC-derived cardiac cells and their products: therapies for cardiac repair

P Menasché - Journal of Molecular and Cellular Cardiology, 2023 - Elsevier
Despite the dramatic improvements in the management of patients with chronic heart failure
which have occurred over the last decades, some of them still exhaust conventional drug …

Dose-dependent improvement of cardiac function in a swine model of acute myocardial infarction after intracoronary administration of allogeneic heart-derived cells

V Crisostomo, C Baez, JL Abad, B Sanchez… - Stem Cell Research & …, 2019 - Springer
Background Allogeneic cardiac-derived progenitor cells (CPC) without immunosuppression
could provide an effective ancillary therapy to improve cardiac function in reperfused …

Cardiac Progenitor Cell Exosomal miR-935 Protects against Oxidative Stress

S Aguilar, P García-Olloqui, L Amigo-Morán, JL Torán… - Cells, 2023 - mdpi.com
Oxidative stress-induced myocardial apoptosis and necrosis are critically involved in
ischemic infarction, and several sources of extracellular vesicles appear to be enriched in …

Cardiomyogenesis modeling using pluripotent stem cells: the role of microenvironmental signaling

A Leitolis, AW Robert, IT Pereira, A Correa… - Frontiers in cell and …, 2019 - frontiersin.org
Pluripotent stem cells (PSC) can be used as a model to study cardiomyogenic differentiation.
In vitro modeling can reproduce cardiac development through modulation of some key …

Therapeutic potential of extracellular vesicles derived from cardiac progenitor cells in rodent models of chemotherapy-induced cardiomyopathy

M Desgres, B Lima Correa, L Petrusca… - Frontiers in …, 2023 - frontiersin.org
Background Current treatments of chemotherapy-induced cardiomyopathy (CCM) are of
limited efficacy. We assessed whether repeated intravenous injections of human …

Search for novel plasma membrane proteins as potential biomarkers in human mesenchymal stem cells derived from dental pulp, adipose tissue, bone marrow, and …

G Akpinar, KK Yoneten, M Kasap, E Karaoz - The Journal of Membrane …, 2021 - Springer
One of the drawbacks preventing the use of mesenchymal stem cells (MSCs) in clinical
practice is the heterogeneous nature of their cultures. MSC cultures are not homogeneously …

[HTML][HTML] Stem cells characterization: OMICS reinforcing analytics

MJ Sebastião, M Serra, P Gomes-Alves… - Current Opinion in …, 2021 - Elsevier
Highlights•Overview of analytics for characterization of stem cells' critical quality
attributes.•Highlight the main challenges for definition of stem cell potency.•Outline the role …

Intracoronary delivery of porcine cardiac progenitor cells overexpressing IGF-1 and HGF in a pig model of sub-acute myocardial infarction

C Prat-Vidal, V Crisóstomo, I Moscoso, C Báez-Díaz… - Cells, 2021 - mdpi.com
Human cardiac progenitor cells (hCPC) are considered a good candidate in cell therapy for
ischemic heart disease, demonstrating capacity to improve functional recovery after …

Comparative proteomic analysis identifies EphA2 as a specific cell surface marker for Wharton's jelly-derived mesenchymal stem cells

A Al Madhoun, SK Marafie, D Haddad… - International journal of …, 2020 - mdpi.com
Wharton's jelly-derived mesenchymal stem cells (WJ-MSCs) are a valuable tool in stem cell
research due to their high proliferation rate, multi-lineage differentiation potential, and …