Comparison of large animal models for acute ischemic stroke: which model to use?

A Taha, J Bobi, R Dammers, RM Dijkhuizen, AY Dreyer… - Stroke, 2022 - Am Heart Assoc
Translation of acute ischemic stroke research to the clinical setting remains limited over the
last few decades with only one drug, recombinant tissue-type plasminogen activator …

Stroke studies in large animals: Prospects of mitochondrial transplantation and enhancing efficiency using hydrogels and nanoparticle-assisted delivery

O Ulger, I Eş, CM Proctor, O Algin - Ageing Research Reviews, 2024 - Elsevier
One of the most frequent reasons of mortality and disability today is acute ischemic stroke,
which occurs by an abrupt disruption of cerebral circulation. The intricate damage …

Functional outcome following stroke thrombectomy in clinical practice

FA Wollenweber, S Tiedt, A Alegiani, B Alber… - Stroke, 2019 - Am Heart Assoc
Background and Purpose—Endovascular treatment for large vessel occlusion in ischemic
stroke has proven to be effective in large clinical trials. We aimed to provide real-world …

Current status of endovascular treatment for acute large vessel occlusion in China: a real-world nationwide registry

B Jia, Z Ren, M Mokin, WS Burgin, CT Bauer, J Fiehler… - Stroke, 2021 - Am Heart Assoc
Background and Purpose: The benefit of endovascular treatment (EVT) for large vessel
occlusion in clinical practice in developing countries like China needs to be confirmed. The …

Time to endovascular treatment and outcome in acute ischemic stroke: MR CLEAN registry results

MJHL Mulder, IGH Jansen, RJB Goldhoorn… - Circulation, 2018 - Am Heart Assoc
Background: Randomized, clinical trials in selected acute ischemic stroke patients reported
that for every hour delay of endovascular treatment (EVT), chances of functional …

Predicting outcome of endovascular treatment for acute ischemic stroke: potential value of machine learning algorithms

HJA Van Os, LA Ramos, A Hilbert… - Frontiers in …, 2018 - frontiersin.org
Background: Endovascular treatment (EVT) is effective for stroke patients with a large vessel
occlusion (LVO) of the anterior circulation. To further improve personalized stroke care, it is …

Downregulation of circular RNA HECTD1 induces neuroprotection against ischemic stroke through the microRNA-133b/TRAF3 pathway

Q Dai, Y Ma, Z Xu, L Zhang, H Yang, Q Liu, J Wang - Life Sciences, 2021 - Elsevier
Abstract Aims Circular RNAs (circRNAs) have been shown to play crucial roles in various
biological processes and human diseases. However, their exact functions in ischemic stroke …

Effect of interhospital transfer on endovascular treatment for acute ischemic stroke

E Venema, AE Groot, HF Lingsma, W Hinsenveld… - Stroke, 2019 - Am Heart Assoc
Background and Purpose—To assess the effect of inter-hospital transfer on time to treatment
and functional outcome after endovascular treatment (EVT) for acute ischemic stroke, we …

Thrombectomy for stroke with large infarct on noncontrast CT: the TESLA randomized clinical trial

R White, K Gembreska, V Chaubal, M AlMajali… - Jama, 2024 - jamanetwork.com
Importance Recent large infarct thrombectomy trials used heterogeneous imaging
modalities and time windows for patient selection. Noncontrast computed tomographic (CT) …

Data-efficient deep learning of radiological image data for outcome prediction after endovascular treatment of patients with acute ischemic stroke

A Hilbert, LA Ramos, HJA van Os… - Computers in biology …, 2019 - Elsevier
Abstract Treatment selection is becoming increasingly more important in acute ischemic
stroke patient care. Clinical variables and radiological image biomarkers (old age, pre …