Alzheimer's disease (AD) is a degenerative neurological disease in elderly individuals.
Subjective cognitive decline (SCD), mild cognitive impairment (MCI) and further …

The global prevalence of dementia is as high as 24 million, and has been predicted to
quadruple by the year 2050. In the US alone, Alzheimer disease (AD)–the most frequent …

Brain network dysfunction is increasingly recognised in Alzheimer's disease (AD). However,
the causes of brain connectivity disruption are still poorly understood. Recently …

Many neurological diseases and delineating pathological regions have been analyzed, and
the anatomical structure of the brain researched with the aid of magnetic resonance imaging …

Importance The extent to which large-caliber axonal degeneration contributes to Alzheimer
disease (AD) progression is unknown. Cerebrospinal fluid (CSF) neurofilament light (NFL) …

Alzheimer's disease is increasingly considered a large-scale network disconnection
syndrome, associated with progressive aggregation of pathological proteins, cortical …

Microglia are the primary immune cell of the brain and function to protect the central nervous
system (CNS) from injury and invading pathogens. In the homeostatic brain, microglia serve …

The structure of the brain is constantly changing from birth throughout the lifetime, meaning
that normal aging, free from dementia, is associated with structural brain changes. This …

Though mild cognitive impairment is an intermediate clinical state between healthy aging
and Alzheimer's disease (AD), there are very few whole-brain voxel-wise diffusion MRI …

Previous research in non-human primates has shown that the superior longitudinal fascicle
(SLF), a major intrahemispheric fiber tract, is actually composed of four separate …