Preclinical models of congestive heart failure, advantages, and limitations for application in clinical practice
M Saura, JL Zamorano, C Zaragoza - Frontiers in physiology, 2022 - frontiersin.org
Congestive heart failure (CHF) has increased over the years, in part because of recent
progress in the management of chronic diseases, thus contributing to the maintenance of an …
progress in the management of chronic diseases, thus contributing to the maintenance of an …
Pulmonary artery banding in sheep: a novel large animal model for congestive hepatopathy
Congestive hepatopathy is becoming increasingly recognized among Fontan-palliated
patients. Elevated central venous pressure is thought to drive the pathologic progression …
patients. Elevated central venous pressure is thought to drive the pathologic progression …
Large animal preclinical investigation into the optimal extracorporeal life support configuration for pulmonary hypertension and right ventricular failure
Introduction Right ventricular failure (RVF) is a major cause of mortality in pulmonary
hypertension (PH). Mechanical circulatory support holds promise for patients with medically …
hypertension (PH). Mechanical circulatory support holds promise for patients with medically …
A large animal model for pulmonary hypertension and right ventricular failure: left pulmonary artery ligation and progressive main pulmonary artery banding in sheep
Decompensated right ventricular failure (RVF) in pulmonary hypertension (PH) is fatal, with
limited medical treatment options. Developing and testing novel therapeutics for PH requires …
limited medical treatment options. Developing and testing novel therapeutics for PH requires …
Ambulatory 7-day mechanical circulatory support in sheep model of pulmonary hypertension and right heart failure
Background Right heart failure is the major cause of death in pulmonary hypertension. Lung
transplantation is the only long-term treatment option for patients who fail medical therapy …
transplantation is the only long-term treatment option for patients who fail medical therapy …
Progression toward decompensated right ventricular failure in the ovine pulmonary hypertension model
R Ukita, A Tumen, JW Stokes, C Pinelli, KR Finnie… - ASAIO …, 2022 - journals.lww.com
Decompensated right ventricular failure (RVF) in patients with pulmonary hypertension (PH)
is fatal, with limited treatment options. Novel mechanical circulatory support systems have …
is fatal, with limited treatment options. Novel mechanical circulatory support systems have …
Swine Model of Myocardial Infarction Induced by Ischemia-Reperfusion and Embolization
R Mazurek, O Bikou, K Ishikawa - Experimental Models of Cardiovascular …, 2024 - Springer
Acute myocardial infarction continues to account for a growing burden of heart failure
worldwide. Despite existing therapies, new approaches for reducing the extent of damage …
worldwide. Despite existing therapies, new approaches for reducing the extent of damage …
A Dynamic Sheep Model to Induce Pulmonary Hypertension and Right Ventricular Failure
CA Johnson Jr, M Cortelli Jr, G Glomp… - Experimental Models of …, 2024 - Springer
Decompensated right ventricular failure (RVF) in pulmonary hypertension (PH) is fatal, with
limited medical treatment options. Developing and testing novel therapeutics for PH requires …
limited medical treatment options. Developing and testing novel therapeutics for PH requires …
Establishment of mouse models for severe pulmonary hypertension through 'double‐hit'strategies
L Chen, X Chen, Y Huang, Z Ma, X Zeng… - Experimental …, 2024 - Wiley Online Library
Mouse models are crucial for understanding pulmonary hypertension (PH) mechanisms and
developing therapies, but existing mouse models under hypoxia only exhibit mild PH. To …
developing therapies, but existing mouse models under hypoxia only exhibit mild PH. To …