Diversity of intrinsically photosensitive retinal ganglion cells: circuits and functions
ML Aranda, TM Schmidt - Cellular and Molecular Life Sciences, 2021 - Springer
The melanopsin-expressing, intrinsically photosensitive retinal ganglion cells (ipRGCs) are
a relatively recently discovered class of atypical ganglion cell photoreceptor. These ipRGCs …
a relatively recently discovered class of atypical ganglion cell photoreceptor. These ipRGCs …
Circadian photoentrainment in mice and humans
RG Foster, S Hughes, SN Peirson - Biology, 2020 - mdpi.com
Light around twilight provides the primary entrainment signal for circadian rhythms. Here we
review the mechanisms and responses of the mouse and human circadian systems to light …
review the mechanisms and responses of the mouse and human circadian systems to light …
Intrinsically photosensitive retinal ganglion cells: many subtypes, diverse functions
For decades, rods and cones were thought to be the only photoreceptors in the mammalian
retina. However, a population of atypical photoreceptive retinal ganglion cells (RGCs) …
retina. However, a population of atypical photoreceptive retinal ganglion cells (RGCs) …
Breast cancer and circadian disruption from electric lighting in the modern world
RG Stevens, GC Brainard, DE Blask… - CA: a cancer journal …, 2014 - Wiley Online Library
Breast cancer is the leading cause of cancer death among women worldwide, and there is
only a limited explanation of why. Risk is highest in the most industrialized countries but also …
only a limited explanation of why. Risk is highest in the most industrialized countries but also …
Regulating the suprachiasmatic nucleus (SCN) circadian clockwork: interplay between cell-autonomous and circuit-level mechanisms
ED Herzog, T Hermanstyne… - Cold Spring …, 2017 - cshperspectives.cshlp.org
The suprachiasmatic nucleus (SCN) is the principal circadian clock of the brain, directing
daily cycles of behavior and physiology. SCN neurons contain a cell-autonomous …
daily cycles of behavior and physiology. SCN neurons contain a cell-autonomous …
Novel insights from a multiomics dissection of the Hayflick limit
The process wherein dividing cells exhaust proliferative capacity and enter into replicative
senescence has become a prominent model for cellular aging in vitro. Despite decades of …
senescence has become a prominent model for cellular aging in vitro. Despite decades of …
Roles of neuropeptides, VIP and AVP, in the mammalian central circadian clock
D Ono, K Honma, S Honma - Frontiers in neuroscience, 2021 - frontiersin.org
In mammals, the central circadian clock is located in the suprachiasmatic nucleus (SCN) of
the hypothalamus. Individual SCN cells exhibit intrinsic oscillations, and their circadian …
the hypothalamus. Individual SCN cells exhibit intrinsic oscillations, and their circadian …
Architecture of retinal projections to the central circadian pacemaker
The suprachiasmatic nucleus (SCN) receives direct retinal input from the intrinsically
photosensitive retinal ganglion cells (ipRGCs) for circadian photoentrainment. Interestingly …
photosensitive retinal ganglion cells (ipRGCs) for circadian photoentrainment. Interestingly …
Diversification of multipotential postmitotic mouse retinal ganglion cell precursors into discrete types
The genesis of broad neuronal classes from multipotential neural progenitor cells has been
extensively studied, but less is known about the diversification of a single neuronal class into …
extensively studied, but less is known about the diversification of a single neuronal class into …
Circuit mechanisms underlying embryonic retinal waves
Spontaneous activity is a hallmark of developing neural systems. In the retina, spontaneous
activity comes in the form of retinal waves, comprised of three stages persisting from …
activity comes in the form of retinal waves, comprised of three stages persisting from …