The concept of the personal vitamin D response index

C Carlberg, A Haq - The Journal of steroid biochemistry and molecular …, 2018 - Elsevier
Humans are able to synthesize vitamin D 3 in their skin when exposed to UV-B, but
seasonal variations, textile coverage and predominant indoor activities often make …

[HTML][HTML] Genome-wide (over) view on the actions of vitamin D

C Carlberg - Frontiers in physiology, 2014 - frontiersin.org
For a global understanding of the physiological impact of the nuclear hormone 1α, 25-
dihydroxyvitamin D3 (1, 25 (OH) 2D3) the analysis of the genome-wide locations of its high …

[HTML][HTML] Disassociation of vitamin D's calcemic activity and non-calcemic genomic activity and individual responsiveness: a randomized controlled double-blind …

A Shirvani, TA Kalajian, A Song, MF Holick - Scientific reports, 2019 - nature.com
The aims of this randomized controlled double-blind clinical trial were to assess the impact
of vitamin D supplementation on calcium metabolism and non-calcemic broad gene …

[HTML][HTML] Vitamin D as a protector of arterial health: potential role in peripheral arterial disease formation

SM Krishna - International Journal of Molecular Sciences, 2019 - mdpi.com
Atherosclerotic occlusive diseases and aneurysms that affect large and medium-sized
arteries outside the cardiac and cerebral circulation are collectively known as peripheral …

[HTML][HTML] Primary Vitamin D Target Genes Allow a Categorization of Possible Benefits of Vitamin D3 Supplementation

C Carlberg, S Seuter, VDF de Mello, U Schwab… - PLoS …, 2013 - journals.plos.org
Vitamin D deficiency has been associated with an increased risk of developing a number of
diseases. Here we investigated samples from 71 pre-diabetic individuals of the VitDmet …

Vitamin D receptor signaling and its therapeutic implications: Genome-wide and structural view

C Carlberg, F Molnár - Canadian journal of physiology and …, 2015 - cdnsciencepub.com
Vitamin D3 is one of the few natural compounds that has, via its metabolite 1α, 25-
dihydroxyvitamin D3 (1, 25 (OH) 2D3) and the transcription factor vitamin D receptor (VDR) …

Increased monocyte‐platelet aggregates and monocyte‐endothelial adhesion in healthy individuals with vitamin D deficiency

HM Tay, WH Yeap, R Dalan, SC Wong… - The FASEB …, 2020 - Wiley Online Library
Vitamin D deficiency is a major public health problem worldwide, linked to several chronic
diseases including cardiovascular diseases. While immunomodulatory effects of vitamin D …

The vitamin D-dependent transcriptome of human monocytes

A Neme, V Nurminen, S Seuter, C Carlberg - The Journal of steroid …, 2016 - Elsevier
Monocytes are important cells of the innate immune system that can differentiate into
macrophages and dendritic cells. The biologically active form of vitamin D, 1α, 25 …

Molecular approaches for optimizing vitamin D supplementation

C Carlberg - Vitamins & Hormones, 2016 - Elsevier
Vitamin D can be synthesized endogenously within UV-B exposed human skin. However,
avoidance of sufficient sun exposure via predominant indoor activities, textile coverage, dark …

Changes in vitamin D target gene expression in adipose tissue monitor the vitamin D response of human individuals

J Ryynänen, A Neme, TP Tuomainen… - Molecular nutrition & …, 2014 - Wiley Online Library
Scope Vitamin D3, its biologically most active metabolite 1α, 25‐dihydroxyvitamin D3 (1, 25
(OH) 2D3), and the vitamin D receptor (VDR) are important for adipose tissue biology …