Cortical gray matter deficits have been found in patients with schizophrenia, with evidence of
progression over time. The aim of this study was to determine the extent of progressive …

Purpose of review. In this review, we provide an update of recent studies on the age of onset
(AOO) of the major mental disorders, with a special focus on the availability and use of …

Although the onset of most mental disorders usually occurs during the first three decades of
life, effective treatment is typically not initiated until a number of years later. Although there is …

Many of the major neuropsychiatric illnesses, including schizophrenia, have a typical age of
onset in late adolescence. Late adolescence may reflect a critical period in brain …

This Practice Parameter reviews the literature on the assessment and treatment of children
and adolescents with schizophrenia. Early-onset schizophrenia is diagnosed using the …

Objective: Treatment of early-onset schizophrenia spectrum psychosis (EOS) is hampered
by limited data on clinical presentation and illness course. We aimed to systematically …

Antipsychotics are efficacious in the treatment of EOS. Given the lack of efficacy differences
between antipsychotics (except for clozapine for treatment-refractory EOS), we propose that …

In einer Vielzahl von Geburtskohortenstudien, epidemiologischen Studien und klinischen
Beobachtungsstudien wurden psychische Erkrankungen bei Kindern, Jugendlichen und …

Objective: Schizophrenia spectrum and other psychotic disorders often have their onset in
adolescence. The sequelae of these illnesses can negatively alter the trajectory of …

Schizophrenia is one of the most prevalent chronic psychiatric disorders that affect 1% of the
world's population. Despite its societal burden, pathophysiology of schizophrenia remains …