Immunotherapy efficacy on mismatch repair-deficient colorectal cancer: From bench to bedside
Colorectal cancers (CRCs) with deficient mismatch repair (dMMR) or microsatellite instability-
high (MSI-H) often have sustained responses to immune checkpoint inhibitors (ICIs) …
high (MSI-H) often have sustained responses to immune checkpoint inhibitors (ICIs) …
BRAF Mutations as Actionable Targets: A Paradigm Shift in the Management of Colorectal Cancer and Novel Avenues
IH Sahin, J Klostergaard - JCO Oncology Practice, 2021 - ascopubs.org
BRAF mutations in colorectal cancer have been studied over the past several decades.
BRAF V600E mutation, a class I mutation, is the most common oncogenic BRAF alteration in …
BRAF V600E mutation, a class I mutation, is the most common oncogenic BRAF alteration in …
Defining the current role of immune checkpoint inhibitors in the treatment of mismatch repair-deficient/microsatellite stability-high colorectal cancer and shedding light …
E Tan, IH Sahin - Expert Review of Gastroenterology & Hepatology, 2021 - Taylor & Francis
Introduction: Mismatch repair deficient (MMR-D)/microsatellite instability-high (MSI-H)
colorectal cancer (CRC) carries unique biologic features including high tumor mutation …
colorectal cancer (CRC) carries unique biologic features including high tumor mutation …
Precision medicine for gastrointestinal cancers: a conference report
IH Sahin - 2020 - Taylor & Francis
As cancer management evolves into precision medicine national/international cancer
meetings bring novel therapeutic approaches and potentially practice-changing results of …
meetings bring novel therapeutic approaches and potentially practice-changing results of …