Virus-like particle vaccines and platforms for vaccine development

M Kheirvari, H Liu, E Tumban - Viruses, 2023 - mdpi.com
Virus-like particles (VLPs) have gained a lot of interest within the past two decades. The use
of VLP-based vaccines to protect against three infectious agents—hepatitis B virus, human …

Hepatitis B virus (HBV) subviral particles as protective vaccines and vaccine platforms

JKT Ho, B Jeevan-Raj, HJ Netter - Viruses, 2020 - mdpi.com
Hepatitis B remains one of the major global health problems more than 40 years after the
identification of human hepatitis B virus (HBV) as the causative agent. A critical turning point …

Development of virus-like particle technology from small highly symmetric to large complex virus-like particle structures

P Pushko, P Pumpens, E Grens - Intervirology, 2013 - karger.com
Virus-like particle (VLP) technology is a promising approach for the construction of novel
vaccines, diagnostic tools, and gene therapy vectors. Initially, VLPs were primarily derived …

Reactive oxygen species and gastric carcinogenesis: The complex interaction between Helicobacter pylori and host

S Wu, Y Chen, Z Chen, F Wei, Q Zhou, P Li… - Helicobacter, 2023 - Wiley Online Library
Helicobacter pylori (H. pylori) is a highly successful human pathogen that colonizes stomach
in around 50% of the global population. The colonization of bacterium induces an …

Potential antigen candidates for subunit vaccine development against Helicobacter pylori infection

M Keikha, M Eslami, B Yousefi… - Journal of cellular …, 2019 - Wiley Online Library
Helicobacter pylori (H. pylori) is a resident bacterium in the stomach that accounts for 75%
cases of gastric cancer. In this review, we comprehensively studied published papers on H …

The study of H. pylori putative candidate factors for single- and multi-component vaccine development

N Mirzaei, F Poursina, S Moghim… - Critical reviews in …, 2017 - Taylor & Francis
Helicobacter pylori has grown to colonize inside the stomach of nearly half of the world's
population, turning into the most prevalent infections in the universe. Medical care failures …

Specific antibodies induced by immunization with hepatitis B virus-like particles carrying hepatitis C virus envelope glycoprotein 2 epitopes show differential …

A Czarnota, A Offersgaard, AF Pihl, J Prentoe, J Bukh… - Vaccines, 2020 - mdpi.com
Hepatitis C virus (HCV) infection with associated chronic liver diseases is a major health
problem worldwide. Here, we designed hepatitis B virus (HBV) small surface antigen …

An intranasal influenza virus vector vaccine protects against Helicobacter pylori in mice

L Nie, Y Huang, Z Cheng, H Luo, Y Zhan… - Journal of …, 2024 - Am Soc Microbiol
Helicobacter pylori is a human pathogen that infects almost half of the population. Antibiotic
resistance in H. pylori threatens health and increases the demand for prophylactic and …

KISS1 can be used as a novel target for developing a DNA immunocastration vaccine in ram lambs

Y Han, G Liu, X Jiang, N Ijaz, B Tesema, G Xie - Vaccine, 2015 - Elsevier
KISS1 gene-encoding kisspeptins are critical for the onset of puberty and control of adult
fertility. This study investigated whether KISS1 can be used as a novel target for …

Hepatitis B virus surface antigen as delivery vector can enhance Chlamydia trachomatis MOMP multi-epitope immune response in mice

S Zhu, Y Feng, P Rao, X Xue, S Chen, WS Li… - Applied microbiology …, 2014 - Springer
Chlamydia trachomatis is the leading cause of sexually transmitted infections worldwide.
There is currently no commercially available vaccine against C. trachomatis. Major outer …