Emerging progress in nausea and vomiting of pregnancy and hyperemesis gravidarum: challenges and opportunities

C Liu, G Zhao, D Qiao, L Wang, Y He, M Zhao… - Frontiers in …, 2022 - frontiersin.org
Nausea and vomiting of pregnancy (NVP) is a common condition that affects up to 70% of
pregnant women. Hyperemesis gravidarum (HG) is considered the serious form of NVP …

Body surface mapping of the stomach: New directions for clinically evaluating gastric electrical activity

DA Carson, G O'Grady, P Du… - …, 2021 - Wiley Online Library
Background Gastric motility disorders, which include both functional and organic etiologies,
are highly prevalent. However, there remains a critical lack of objective biomarkers to guide …

Spatial patterns from high-resolution electrogastrography correlate with severity of symptoms in patients with functional dyspepsia and gastroparesis

AA Gharibans, TP Coleman, H Mousa… - Clinical Gastroenterology …, 2019 - Elsevier
Background & Aims Invasive gastric electrical mapping has revealed spatial abnormalities of
the slow wave in subjects with gastroparesis and functional gastrointestinal disorders …

The gastric conduction system in health and disease: a translational review

G O'Grady, AA Gharibans, P Du… - American Journal of …, 2021 - journals.physiology.org
Gastric peristalsis is critically dependent on an underlying electrical conduction system.
Recent years have witnessed substantial progress in clarifying the operations of this system …

Validation of noninvasive body-surface gastric mapping for detecting gastric slow-wave spatiotemporal features by simultaneous serosal mapping in porcine

S Calder, LK Cheng, CN Andrews… - American Journal …, 2022 - journals.physiology.org
Gastric disorders are increasingly prevalent, but reliable noninvasive tools to objectively
assess gastric function are lacking. Body-surface gastric mapping (BSGM) is a noninvasive …

Strategies to refine gastric stimulation and pacing protocols: experimental and modeling approaches

LK Cheng, ND Nagahawatte, R Avci, P Du… - Frontiers in …, 2021 - frontiersin.org
Gastric pacing and stimulation strategies were first proposed in the 1960s to treat motility
disorders. However, there has been relatively limited clinical translation of these techniques …

SoGut: A soft robotic gastric simulator

Y Dang, Y Liu, R Hashem, D Bhattacharya, J Allen… - Soft robotics, 2021 - liebertpub.com
The human stomach breaks down and transports food by coordinated radial contractions of
the gastric walls. The radial contractions periodically propagate through the stomach and …

Theranostic gastrointestinal residence systems

B Ying, H Huang, Y Su, JG Howarth, Z Gu, K Nan - Device, 2023 - cell.com
Gastrointestinal (GI) residence systems that integrate functions such as sensing, stimulation,
and drug delivery hold promise for intervening in and treating chronic GI conditions …

Sorss: A soft robot for bio-mimicking stomach anatomy and motility

R Hashem, S Kazemi, M Stommel, LK Cheng, W Xu - Soft robotics, 2023 - liebertpub.com
A human stomach is an organ in the digestive system that breaks down foods by
physiological digestion, including mechanical and chemical functions. The mechanical …

Optimization of pacing parameters to entrain slow wave activity in the pig jejunum

ND Nagahawatte, R Avci, N Paskaranandavadivel… - Scientific Reports, 2024 - nature.com
Pacing has been proposed as a therapy to restore function in motility disorders associated
with electrical dysrhythmias. The spatial response of bioelectrical activity in the small …