[HTML][HTML] Role of prostaglandin E2 in tissue repair and regeneration
H Cheng, H Huang, Z Guo, Y Chang, Z Li - Theranostics, 2021 - ncbi.nlm.nih.gov
Tissue regeneration following injury from disease or medical treatment still represents a
challenge in regeneration medicine. Prostaglandin E2 (PGE2), which involves diverse …
challenge in regeneration medicine. Prostaglandin E2 (PGE2), which involves diverse …
[HTML][HTML] Reactive oxygen species-based nanomaterials for the treatment of myocardial ischemia reperfusion injuries
Interventional coronary reperfusion strategies are widely adopted to treat acute myocardial
infarction, but morbidity and mortality of acute myocardial infarction are still high …
infarction, but morbidity and mortality of acute myocardial infarction are still high …
Minimally invasive delivery of therapeutic agents by hydrogel injection into the pericardial cavity for cardiac repair
Cardiac patches are an effective way to deliver therapeutics to the heart. However, such
procedures are normally invasive and difficult to perform. Here, we develop and test a …
procedures are normally invasive and difficult to perform. Here, we develop and test a …
Cardiac fibrosis: Myofibroblast-mediated pathological regulation and drug delivery strategies
Cardiac fibrosis remains an unresolved problem in heart diseases. After initial injury, cardiac
fibroblasts (CFs) are activated and subsequently differentiate into myofibroblasts (myoFbs) …
fibroblasts (CFs) are activated and subsequently differentiate into myofibroblasts (myoFbs) …
Drug targeting via platelet membrane–coated nanoparticles
Platelets exhibit distinct surface moieties responsible for modulating their adhesion to
various disease‐relevant substrates involving vascular damage, immune evasion, and …
various disease‐relevant substrates involving vascular damage, immune evasion, and …
[HTML][HTML] Biomimetic platelet membrane-coated nanoparticles for targeted therapy
H Han, R Bartolo, J Li, MA Shahbazi… - European Journal of …, 2022 - Elsevier
The development of cell membrane-modified biomimetic nanoparticles has extensively
increased during the past years due to their exceptional biocompatibility, evasion from the …
increased during the past years due to their exceptional biocompatibility, evasion from the …
A minimally invasive exosome spray repairs heart after myocardial infarction
Myocardial infarction (MI) remains the most common cause of death worldwide. Many MI
survivors will suffer from recurrent heart failure (HF), which has been recognized as a …
survivors will suffer from recurrent heart failure (HF), which has been recognized as a …
An off-the-shelf artificial cardiac patch improves cardiac repair after myocardial infarction in rats and pigs
Cell therapy has been a promising strategy for cardiac repair after injury or infarction;
however, low retention and engraftment of transplanted cells limit potential therapeutic …
however, low retention and engraftment of transplanted cells limit potential therapeutic …
Platelet membrane and stem cell exosome hybrids enhance cellular uptake and targeting to heart injury
Exosomes from mesenchymal stem cells have been widely studied as therapeutics to treat
myocardial infarction. However, exosomes injected for therapeutic purposes face a number …
myocardial infarction. However, exosomes injected for therapeutic purposes face a number …
Platelet-armored nanoplatform to harmonize janus-faced IFN-γ against tumor recurrence and metastasis
Q Li, Y Zhou, W He, X Ren, M Zhang, Y Jiang… - Journal of Controlled …, 2021 - Elsevier
Abstract Interferon-γ (IFN-γ) plays contradictory roles in tumor immunology:(I) to activate
positive host's immunity for eliminating tumor;(II) to induce negative adaptive immune …
positive host's immunity for eliminating tumor;(II) to induce negative adaptive immune …