Natural products as α-amylase and α-glucosidase inhibitors and their hypoglycaemic potential in the treatment of diabetes: an update
R Tundis, MR Loizzo, F Menichini - Mini reviews in medicinal …, 2010 - ingentaconnect.com
The inhibition of α-glucosidase and α-amylase, enzymes involved in the digestion of
carbohydrates, can significantly reduce the post-prandial increase of blood glucose and …
carbohydrates, can significantly reduce the post-prandial increase of blood glucose and …
Salmonella Produces an O-Antigen Capsule Regulated by AgfD and Important for Environmental Persistence
In this study, we show that Salmonella produces an O-antigen capsule coregulated with the
fimbria-and cellulose-associated extracellular matrix. Structural analysis of purified …
fimbria-and cellulose-associated extracellular matrix. Structural analysis of purified …
[HTML][HTML] Mechanistic and structural analysis of a family 31 α-glycosidase and its glycosyl-enzyme intermediate
We have determined the first structure of a family 31 α-glycosidase, that of YicI from
Escherichia coli, both free and trapped as a 5-fluoroxylopyranosyl-enzyme intermediate via …
Escherichia coli, both free and trapped as a 5-fluoroxylopyranosyl-enzyme intermediate via …
[HTML][HTML] Development of a thermophilic coculture for corn fiber conversion to ethanol
The fiber in corn kernels, currently unutilized in the corn to ethanol process, represents an
opportunity for introduction of cellulose conversion technology. We report here that …
opportunity for introduction of cellulose conversion technology. We report here that …
Structure of the Sulfolobus solfataricus α-glucosidase: implications for domain conservation and substrate recognition in GH31
The crystal structure of α-glucosidase MalA from Sulfolobus solfataricus has been
determined at 2.5 Å resolution. It provides a structural model for enzymes representing the …
determined at 2.5 Å resolution. It provides a structural model for enzymes representing the …
Distinct evolutionary trajectories in the Escherichia coli pangenome occur within sequence types
EA Cummins, RJ Hall, C Connor… - Microbial …, 2022 - microbiologyresearch.org
The Escherichia coli species contains a diverse set of sequence types and there remain
important questions regarding differences in genetic content within this population that need …
important questions regarding differences in genetic content within this population that need …
[HTML][HTML] The genomes of polyextremophilic cyanidiales contain 1% horizontally transferred genes with diverse adaptive functions
The role and extent of horizontal gene transfer (HGT) in eukaryotes are hotly disputed topics
that impact our understanding of the origin of metabolic processes and the role of organelles …
that impact our understanding of the origin of metabolic processes and the role of organelles …
Function and structure studies of GH family 31 and 97 α-glycosidases
M Okuyama - Bioscience, biotechnology, and biochemistry, 2011 - academic.oup.com
A huge number of glycoside hydrolases are classified into the glycoside hydrolase family
(GH family) based on their amino-acid sequence similarity. The glycoside hydrolases acting …
(GH family) based on their amino-acid sequence similarity. The glycoside hydrolases acting …
YihQ is a sulfoquinovosidase that cleaves sulfoquinovosyl diacylglyceride sulfolipids
Sulfoquinovose is produced by photosynthetic organisms at a rate of 1010 tons per annum
and is degraded by bacteria as a source of carbon and sulfur. We have identified …
and is degraded by bacteria as a source of carbon and sulfur. We have identified …
Structural and enzymatic characterization of a glycoside hydrolase family 31 α-xylosidase from Cellvibrio japonicus involved in xyloglucan saccharification
J Larsbrink, A Izumi, FM Ibatullin, A Nakhai… - Biochemical …, 2011 - portlandpress.com
The desire for improved methods of biomass conversion into fuels and feedstocks has re-
awakened interest in the enzymology of plant cell wall degradation. The complex …
awakened interest in the enzymology of plant cell wall degradation. The complex …