Clostridium perfringens is an extremely versatile pathogen of humans and livestock, causing
wound infections like gas gangrene (clostridial myonecrosis), enteritis/enterocolitis …

Maintaining a healthy gut environment is a prerequisite for sustainable animal production.
The gut plays a key role in the digestion and absorption of nutrients and constitutes an initial …

For over 30 years a phospholipase C enzyme called alpha-toxin was thought to be the key
virulence factor in necrotic enteritis caused by Clostridium perfringens. However, using a …

Clostridium perfringens uses its large arsenal of protein toxins to produce histotoxic,
neurologic and intestinal infections in humans and animals. The major toxins involved in …

Necrotic enteritis (NE) is one of the most important enteric diseases in poultry and is a high
cost to the industry worldwide. It is caused by avian-specific, Necrotic Enteritis Beta toxin …

In both humans and animals, Clostridium perfringens is an important cause of histotoxic
infections and diseases originating in the intestines, such as enteritis and enterotoxemia …

Bacterial sphingomyelinases and phospholipases are a heterogeneous group of esterases
which are usually surface associated or secreted by a wide variety of Gram-positive and …

The use of in-feed antibiotics has until now been the main strategy for controlling Clostridium
perfringens-associated necrotic enteritis in poultry. But approvals for the inclusion of non …

Clostridium perfringens is a gram-positive anaerobic rod that is classified into 5 toxinotypes
(A, B, C, D, and E) according to the production of 4 major toxins, namely alpha (CPA), beta …

Two experiments were conducted to examine the effect of the level of dietary crude protein
and protein source on intestinal populations of Clostridium perfringens in broilers. In …