Ursolic acid in cancer prevention and treatment: molecular targets, pharmacokinetics and clinical studies

MK Shanmugam, X Dai, AP Kumar, BKH Tan… - Biochemical …, 2013 - Elsevier
Discovery of bioactive molecules and elucidation of their molecular mechanisms open up an
enormous opportunity for the development of improved therapy for different inflammatory …

Cytotoxic activity of ursolic acid derivatives obtained by isolation and oxidative derivatization

K Mazumder, K Tanaka, K Fukase - Molecules, 2013 - mdpi.com
Structure-activity relationships of ursane-type pentacyclic triterpenes obtained from natural
sources and by chemical derivatization are reviewed. Ursolic acid, corosolic acid, and a new …

Dual function of lectins—new perspectives in targeted photodynamic therapy

V Bogoeva, L Petrova, J Bouckaert… - Journal of Porphyrins …, 2019 - World Scientific
Porphyrins and phthalocyanines are photosensitizers (PS) that are used in clinical imaging,
detection of cancer cells and are particularly applied in photodynamic therapy (PDT). Many …

Easy access to powerful ruthenium phthalocyanine high-oxidized species

SV Zaitseva, EY Tyulyaeva, DV Tyurin, SA Zdanovich… - Polyhedron, 2022 - Elsevier
Ruthenium (III) phthalocyanine was synthesized using the solvent assisted approach from
RuCl 3· nH 2 O first compound with chlorinated solvents was observed to result in …

Sulfamates of methyl triterpenoates are effective and competitive inhibitors of carbonic anhydrase II

S Schwarz, S Sommerwerk, SD Lucas, L Heller… - European Journal of …, 2014 - Elsevier
Carbonic anhydrase II, belonging to one of the most important enzyme groups of the human
body, is a well-studied isozyme from the family of the carbonic anhydrases. Since it is …

Modern approaches in the synthesis of noble metal porphyrins for their practical application

EY Tyulyaeva - Russian Journal of Inorganic Chemistry, 2019 - Springer
Being inert in the elemental state and as compounds, noble metals—ruthenium, osmium,
rhodium, iridium, palladium, platinum, silver, and gold—and rhenium, whose compounds …

Selective oxidation of lupeol by iodosylbenzene catalyzed by manganese porphyrins

DC da Silva Martins, FC Silva, AM Meireles… - Catalysis …, 2016 - Elsevier
Manganese porphyrin-catalyzed oxidation of lupeol by iodosylbenzene was achieved under
mild conditions with low isolated yields but with remarkable selectivity, depending on the …

Biomimetic chemical reactions with natural products using metalloporphyrins and salen complexes as catalysts: a brief review

RCN Sousa, VPP Confessor… - Chemistry & …, 2024 - Wiley Online Library
The cytochrome P450 is a superfamily of hemoproteins mainly present in the liver and are
versatile biocatalysts. They participate in the primary metabolism and biosynthesis of various …

New Trends in the Direct Synthesis of Phthalocyanine/Porphyrin Complexes

TN Lomova, EY Tyulyaeva - Direct Synthesis of Metal Complexes, 2018 - Elsevier
This chapter represents the results of the analysis of new trends in metal phyhalocyanines
(MPcs) direct synthesis. The preparation of MPcs from metal alloys and metal carbonyls …

Oxidative lactonization of oleanane and ursane acids by treating with ozone

EF Husnutdinova, AN Lobov, OS Kukovinets… - Russian Journal of …, 2015 - Springer
Features of process of oxidative lactonization of 3-oxooleanolic and 3-oxoursolic acids
under treatment with ozone were established. The similarity of the processes consists in …