Background Xpert MTB/RIF (Xpert MTB/RIF) and Xpert MTB/RIF Ultra (Xpert Ultra), the
newest version, are the only World Health Organization (WHO)‐recommended rapid tests …

Molecular tests for tuberculosis (TB) have the potential to help reach the three million people
with TB who are undiagnosed or not reported each year and to improve the quality of care …

Background Current diagnostics for HIV-associated tuberculosis are suboptimal, with
missed diagnoses contributing to high hospital mortality and approximately 374 000 annual …

Background Xpert MTB/RIF and Xpert MTB/RIF Ultra (Xpert Ultra) are World Health
Organization (WHO)‐recommended rapid tests that simultaneously detect tuberculosis and …

Background Suboptimal tuberculosis (TB) diagnostics and HIV contribute to the high global
burden of TB. We investigated costs and yield from systematic HIV-TB screening, including …

BACKGROUND Point-of-care technology (POCT) provides actionable information at the site
of care to allow rapid clinical decision-making. With healthcare emphasis shifting toward …

Summary Background Xpert MTB/RIF, the most widely used automated nucleic acid
amplification test for tuberculosis, is available in more than 130 countries. Although …

More sensitive tests are needed for the diagnosis of smear-negative and HIV-associated
tuberculosis. This study compares the sensitivities and specificities of three molecular tests …

Tuberculosis (TB) remains a significant, yet under-recognized cause of death in the pediatric
population, with a WHO estimate of 1 million new cases of childhood TB in 2016 resulting in …

SETTING: In 2005, in response to the increasing prevalence of rifampicin-resistant
tuberculosis (RR-TB) and poor treatment outcomes, Rwanda initiated the programmatic …