Oral cancers are the sixth most frequent cancer with a high mortality rate. Oral squamous
cell carcinoma accounts for more than 90% of all oral cancers. Standard methods used to …

Abstract Knowledge of epigenetic alterations in disease is rapidly increasing owing to the
development of genome-wide techniques for their identification. The ever-growing number …

Advances in genomics, proteomics and molecular pathology have generated many
candidate biomarkers with potential clinical value. Their use for cancer staging and …

The past few years have seen an explosion of interest in the epigenetics of cancer. This has
been a consequence of both the exciting coalescence of the chromatin and DNA …

We have come a long way since the first reports of the existence of aberrant DNA
methylation in human cancer. Hypermethylation of CpG islands located in the promoter …

Head and neck cancers include neoplasms of the oral cavity, pharynx, and larynx. The risk
of these cancers is strongly associated with smoking and alcohol ingestion. There have …

In the past decade, there have been fundamental advances in our understanding of genetic
factors that contribute to the inflammatory bowel diseases (IBDs) Crohn's disease and …

The prototypic head and neck squamous cell carcinoma (HNSCC) arises from the mucosal
lining of the upper aerodigestive tract, demonstrates squamous differentiation …

Purpose: This study aims to explore the presence of informative protein biomarkers in the
human saliva proteome and to evaluate their potential for detection of oral squamous cell …

Introduction Oral cancer is one of the most common cancers and it constitutes a major health
problem particularly in developing countries. It is one of the leading causes of death …