Nonalcoholic steatohepatitis-related hepatocellular carcinoma: pathogenesis and treatment

JM Llovet, CE Willoughby, AG Singal… - Nature reviews …, 2023 - nature.com
Nonalcoholic fatty liver disease (NAFLD), including its more severe manifestation,
nonalcoholic steatohepatitis (NASH), has a global prevalence of 20–25% and is a major …

[HTML][HTML] Hepatocellular carcinoma

JM Llovet, RK Kelley, A Villanueva, AG Singal… - Nature reviews Disease …, 2021 - nature.com
Liver cancer remains a global health challenge, with an estimated incidence of> 1 million
cases by 2025. Hepatocellular carcinoma (HCC) is the most common form of liver cancer …

AASLD practice guidance on prevention, diagnosis, and treatment of hepatocellular carcinoma

AG Singal, JM Llovet, M Yarchoan, N Mehta… - Hepatology, 2023 - journals.lww.com
This guidance document provides an updated approach to the prevention, diagnosis, and
treatment of hepatocellular carcinoma (HCC). The prior American Association for the Study …

Evidence-based clinical practice guidelines for Liver Cirrhosis 2020

H Yoshiji, S Nagoshi, T Akahane, Y Asaoka… - Journal of …, 2021 - Springer
The first edition of the clinical practice guidelines for liver cirrhosis was published in 2010,
and the second edition was published in 2015 by the Japanese Society of Gastroenterology …

Global epidemiology and genetics of hepatocellular carcinoma

MR Toh, EYT Wong, SH Wong, AWT Ng, LH Loo… - Gastroenterology, 2023 - Elsevier
Hepatocellular carcinoma (HCC) is one of the leading cancers worldwide. Classically, HCC
develops in genetically susceptible individuals who are exposed to risk factors, especially in …

[HTML][HTML] Lipid alterations in chronic liver disease and liver cancer

B Paul, M Lewinska, JB Andersen - JHEP reports, 2022 - Elsevier
Lipids are a complex and diverse group of molecules with crucial roles in many
physiological processes, as well as in the onset, progression, and maintenance of cancers …

Epidemiology of hepatocellular carcinoma

KA McGlynn, JL Petrick, HB El‐Serag - Hepatology, 2021 - Wiley Online Library
Liver cancer is a major contributor to the worldwide cancer burden. Incidence rates of this
disease have increased in many countries in recent decades. As the principal histologic type …

Liver fibrosis: mechanistic concepts and therapeutic perspectives

N Roehlen, E Crouchet, TF Baumert - Cells, 2020 - mdpi.com
Liver fibrosis due to viral or metabolic chronic liver diseases is a major challenge of global
health. Correlating with liver disease progression, fibrosis is a key factor for liver disease …

Epidemiology and surveillance for hepatocellular carcinoma: New trends

AG Singal, P Lampertico, P Nahon - Journal of hepatology, 2020 - Elsevier
The burden of hepatocellular carcinoma (HCC) is highest in East Asia and Africa, although
its incidence and mortality are rapidly rising in the United States and Europe. With the …

A global view of hepatocellular carcinoma: trends, risk, prevention and management

JD Yang, P Hainaut, GJ Gores, A Amadou… - Nature reviews …, 2019 - nature.com
Hepatocellular carcinoma (HCC) is the fourth most common cause of cancer-related death
worldwide. Risk factors for HCC include chronic hepatitis B and hepatitis C, alcohol …