Between a bug and a hard place: Trypanosoma cruzi genetic diversity and the clinical outcomes of Chagas disease
LA Messenger, MA Miles, C Bern - Expert review of anti-infective …, 2015 - Taylor & Francis
Over the last 30 years, concomitant with successful transnational disease control programs
across Latin America, Chagas disease has expanded from a neglected, endemic parasitic …
across Latin America, Chagas disease has expanded from a neglected, endemic parasitic …
Pathogenesis of chagas' disease: parasite persistence and autoimmunity
ARL Teixeira, MM Hecht, MC Guimaro… - Clinical microbiology …, 2011 - Am Soc Microbiol
Acute Trypanosoma cruzi infections can be asymptomatic, but chronically infected
individuals can die of Chagas' disease. The transfer of the parasite mitochondrial kinetoplast …
individuals can die of Chagas' disease. The transfer of the parasite mitochondrial kinetoplast …
Advanced molecular diagnostic techniques for detection of food-borne pathogens: Current applications and future challenges
S Umesha, HM Manukumar - Critical Reviews in Food Science and …, 2018 - Taylor & Francis
The elimination of disease-causing microbes from the food supply is a primary goal and this
review deals with the overall techniques available for detection of food-borne pathogens …
review deals with the overall techniques available for detection of food-borne pathogens …
Invasion and intracellular survival by protozoan parasites
L David Sibley - Immunological reviews, 2011 - Wiley Online Library
Intracellular parasitism has arisen only a few times during the long ancestry of protozoan
parasites including in diverse groups such as microsporidians, kinetoplastids, and …
parasites including in diverse groups such as microsporidians, kinetoplastids, and …
Trypanosoma cruzi: genetic structure of populations and relevance of genetic variability to the pathogenesis of Chagas disease
Chagas disease, caused by the protozoan Trypanosoma cruzi, has a variable clinical
course, ranging from symptomless infection to severe chronic disease with cardiovascular or …
course, ranging from symptomless infection to severe chronic disease with cardiovascular or …
Parasite persistence correlates with disease severity and localization in chronic Chagas' disease
L Zhang, RL Tarleton - The Journal of infectious diseases, 1999 - academic.oup.com
The protozoan parasite Trypanosoma cruzi infects up to 20 million people in Latin America,
and the resulting disease (Chagas' disease) is a leading cause of heart disease and death …
and the resulting disease (Chagas' disease) is a leading cause of heart disease and death …
The Trypanosoma cruzi–host-cell interplay: location, invasion, retention
LO Andrade, NW Andrews - Nature Reviews Microbiology, 2005 - nature.com
Chagas disease is a debilitating human illness caused by infection with the protozoan
Trypanosoma cruzi. A capacity to invade and replicate within many different cell types is a …
Trypanosoma cruzi. A capacity to invade and replicate within many different cell types is a …
Genetic characterization of Trypanosoma cruzi directly from tissues of patients with chronic Chagas disease: differential distribution of genetic types into diverse …
AR Vago, LO Andrade, AA Leite, DÁ Reis… - The American journal of …, 2000 - Elsevier
We have previously shown that a low-stringency single-specific primer–polymerase chain
reaction (LSSP-PCR) is a highly sensitive and reproducible technique for the genetic …
reaction (LSSP-PCR) is a highly sensitive and reproducible technique for the genetic …
Trypanosoma cruzi–Infected Cardiomyocytes Produce Chemokines and Cytokines That Trigger Potent Nitric Oxide–Dependent Trypanocidal Activity
FS Machado, GA Martins, JCS Aliberti… - Circulation, 2000 - Am Heart Assoc
Background—The pathogenesis of myocarditis that occurs in Trypanosoma cruzi–infected
mice is still poorly understood. Therefore, it is important to know the mediators that trigger …
mice is still poorly understood. Therefore, it is important to know the mediators that trigger …
Applications of PCR-based tools for detection and identification of animal trypanosomes: a review and perspectives
M Desquesnes, AMR Dávila - Veterinary parasitology, 2002 - Elsevier
This paper aims to review the applications of the polymerase chain reaction (PCR) for the
detection and identification of trypanosomes in animals. The diagnosis of trypanosomes …
detection and identification of trypanosomes in animals. The diagnosis of trypanosomes …