Diffuse optical imaging and spectroscopy of the female breast is an area of active research.
We review the present status of this field and discuss the broad range of methodologies and …

Optical imaging involves the propagation of light through tissue. Current optical breast
imaging technologies, including diffuse optical spectroscopy, diffuse optical tomography …

Time-correlated single photon counting (TCSPC) was born 54 years ago, in 1960, when
Bollinger and Thomas published a paper on the 'Measurement of Time Dependence of …

We acquired images of breast malignancies using the Twente photoacoustic mammoscope
(PAM), to obtain more information about the clinical feasibility and limitations of …

Approximately 8–20% of breast cancer patients receiving neoadjuvant chemotherapy fail to
achieve a measurable response and endure toxic side effects without benefit. Most clinical …

Purpose Photoacoustic tomography can image the hemoglobin distribution and oxygenation
state inside tissue with high spatial resolution. The purpose of this study is to investigate its …

Near-infrared diffuse optical tomography (DOT) has demonstrated a great potential as an
adjunct modality for differentiation of malignant and benign breast lesions and for monitoring …

Purpose To assess initial breast tumor hemoglobin (Hb) content before the initiation of
neoadjuvant chemotherapy, monitor the Hb changes at the end of each treatment cycle, and …

A machine learning model with physical constraints (ML-PC) is introduced to perform diffuse
optical tomography (DOT) reconstruction. DOT reconstruction is an ill-posed and under …

Optical methods to detect breast cancer on the basis of its increased opacity have been
explored for some time. These methods have matured to a point in which they are capable of …