Inflammation is central to pathogenic processes in diabetes mellitus and the metabolic
syndrome and particularly implicates innate immunity in the development of complications …

Lipid metabolic abnormalities have emerged as potential risk factors for the development
and progression of diabetic complications, including diabetic retinopathy (DR). This review …

The most common cause of untreatable vision loss is dysfunction of the retina. Conditions,
such as age-related macular degeneration, diabetic retinopathy and glaucoma remain …

Despite advancements in wound care, healing of chronic diabetic wounds remains a great
challenge for the clinical fraternity because of the intricacies of the healing process. Due to …

Diabetic retinopathy (DR) affects over 93 million people worldwide and is the number one
cause of blindness among working age adults. These indicators coupled with the projected …

Abstract Background/Aims: The treatment options for diabetic retinopathy (DR) are limited.
Mesenchymal stem cells (MSCs) are a promising treatment option for diabetes and its …

Diabetic retinopathy (DR), a complication of diabetes, is one of the leading causes of
blindness in working-age adults. The pathology of the disease prevents the endogenous …

Activation of pro-inflammatory and pro-angiogenic pathways in the retina and the bone
marrow contributes to pathogenesis of diabetic retinopathy. We identified miR-15a as key …

The metabolically active retina obtains essential lipids by endogenous biosynthesis and
from the systemic circulation. Clinical studies provide limited and sometimes conflicting …

Abstract Angiotensin-converting enzyme 2 (ACE2) is the primary enzyme of the
vasoprotective axis of the renin angiotensin system (RAS). We tested the hypothesis that …