Unraveling treatment response in multiple sclerosis: a clinical and MRI challenge

C Gasperini, L Prosperini, M Tintoré, MP Sormani… - Neurology, 2019 - AAN Enterprises
Over the last few decades, the improved diagnostic criteria, the wide use of MRI, and the
growing availability of effective pharmacologic treatments have led to substantial advances …

[HTML][HTML] Automated MS lesion detection and segmentation in clinical workflow: a systematic review.

F Spagnolo, A Depeursinge, S Schädelin, A Akbulut… - NeuroImage: Clinical, 2023 - Elsevier
Introduction: Over the past few years, the deep learning community has developed and
validated a plethora of tools for lesion detection and segmentation in Multiple Sclerosis …

[HTML][HTML] ExploreASL: an image processing pipeline for multi-center ASL perfusion MRI studies

HJMM Mutsaerts, J Petr, P Groot, P Vandemaele… - Neuroimage, 2020 - Elsevier
Arterial spin labeling (ASL) has undergone significant development since its inception, with
a focus on improving standardization and reproducibility of its acquisition and quantification …

Brain and lesion segmentation in multiple sclerosis using fully convolutional neural networks: a large-scale study

RE Gabr, I Coronado, M Robinson… - Multiple Sclerosis …, 2020 - journals.sagepub.com
Objective: To investigate the performance of deep learning (DL) based on fully convolutional
neural network (FCNN) in segmenting brain tissues in a large cohort of multiple sclerosis …

Performance of five automated white matter hyperintensity segmentation methods in a multicenter dataset

R Heinen, MD Steenwijk, F Barkhof, JM Biesbroek… - Scientific reports, 2019 - nature.com
White matter hyperintensities (WMHs) are a common manifestation of cerebral small vessel
disease, that is increasingly studied with large, pooled multicenter datasets. This data …

Accuracy and reproducibility of automated white matter hyperintensities segmentation with lesion segmentation tool: A European multi-site 3T study

F Ribaldi, D Altomare, J Jovicich, C Ferrari… - Magnetic resonance …, 2021 - Elsevier
Brain vascular damage accumulate in aging and often manifest as white matter
hyperintensities (WMHs) on MRI. Despite increased interest in automated methods to …

BIANCA‐MS: An optimized tool for automated multiple sclerosis lesion segmentation

G Gentile, M Jenkinson, L Griffanti… - Human Brain …, 2023 - Wiley Online Library
In this work we present BIANCA‐MS, a novel tool for brain white matter lesion segmentation
in multiple sclerosis (MS), able to generalize across both the wide spectrum of MRI …

Frontal white matter hyperintensities and executive functioning performance in older adults

EM Boutzoukas, A O'Shea, A Albizu… - Frontiers in aging …, 2021 - frontiersin.org
Frontal lobe structures decline faster than most other brain regions in older adults. Age-
related change in the frontal lobe is associated with poorer executive function (eg, working …

Automatic brain lesion segmentation on standard magnetic resonance images: a scoping review

E Gryska, J Schneiderman, I Björkman-Burtscher… - BMJ open, 2021 - bmjopen.bmj.com
Objectives Medical image analysis practices face challenges that can potentially be
addressed with algorithm-based segmentation tools. In this study, we map the field of …

Segmentation of white matter lesions in multicentre FLAIR MRI

A Khademi, A Gibicar, G Arezza, J DiGregorio… - Neuroimage …, 2021 - Elsevier
White matter lesions (WML) in the brain are thought to be related to ischemic processes,
demyelination, and axonal degeneration. The presence of WML predict cognitive decline …