[HTML][HTML] Unraveling the role of antimicrobial peptides in insects

S Stączek, M Cytryńska… - International journal of …, 2023 - mdpi.com
Antimicrobial peptides (AMPs) are short, mainly positively charged, amphipathic molecules.
AMPs are important effectors of the immune response in insects with a broad spectrum of …

[HTML][HTML] Modeling the neuroimmune system in Alzheimer's and Parkinson's diseases

W Balestri, R Sharma, VA da Silva, BC Bobotis… - Journal of …, 2024 - Springer
Parkinson's disease (PD) and Alzheimer's disease (AD) are neurodegenerative disorders
caused by the interaction of genetic, environmental, and familial factors. These diseases …

[HTML][HTML] Dual Oxidase, a Hydrogen-Peroxide-Producing Enzyme, Regulates Neuronal Oxidative Damage and Animal Lifespan in Drosophila melanogaster

M Baek, W Jang, C Kim - Cells, 2022 - mdpi.com
Reducing the oxidative stress in neurons extends lifespan in Drosophila melanogaster,
highlighting the crucial role of neuronal oxidative damage in lifespan determination …

[HTML][HTML] Pan-neuronal expression of human mutant SOD1 in Drosophila impairs survival and motor performance, induces early neuroinflammation and chromosome …

F Liguori, F Alberti, S Amadio, DF Angelini… - … et Biophysica Acta (BBA …, 2024 - Elsevier
Several mutations in the SOD1 gene encoding for the antioxidant enzyme Superoxide
Dismutase 1, are associated with amyotrophic lateral sclerosis, a rare and devastating …

NADPH Oxidases in Arthropods

ACP Gandara, PL Oliveira - NADPH Oxidases Revisited: From Function to …, 2023 - Springer
Arthropods, especially insects, have been used as physiological models for over a century.
Once the microbicidal action of reactive oxygen species produced by mammalian …

The Different Molecular Targets and Its Significant Role in Alzheimer's Disease: A Review

P Perumal, M Pichaivel - Asian Journal of Medicine and …, 2024 - journal.unisza.edu.my
Alzheimer's disease is a severe neurodegenerative brain illness that affects the majority of
the older population. Alzheimer's disease has become a substantial public health problem …