The DNA methylation landscape in cancer
As one of the most abundant and well-studied epigenetic modifications, DNA methylation
plays an essential role in normal development and cellular biology. Global alterations to the …
plays an essential role in normal development and cellular biology. Global alterations to the …
[HTML][HTML] Biomarkers of nutrition for development—folate review
Abstract The Biomarkers of Nutrition for Development (BOND) project is designed to provide
evidence-based advice to anyone with an interest in the role of nutrition in health …
evidence-based advice to anyone with an interest in the role of nutrition in health …
DNA methylation methods: Global DNA methylation and methylomic analyses
S Li, TO Tollefsbol - Methods, 2021 - Elsevier
DNA methylation provides a pivotal layer of epigenetic regulation in eukaryotes that has
significant involvement for numerous biological processes in health and disease. The …
significant involvement for numerous biological processes in health and disease. The …
[HTML][HTML] MYC-driven accumulation of 2-hydroxyglutarate is associated with breast cancer prognosis
Metabolic profiling of cancer cells has recently been established as a promising tool for the
development of therapies and identification of cancer biomarkers. Here we characterized the …
development of therapies and identification of cancer biomarkers. Here we characterized the …
Physiology of Folate and Vitamin B 12 in Health and Disease
PJ Stover - Nutrition reviews, 2004 - academic.oup.com
Folate is a water-soluble B-vitamin and enzymatic cofactor that is necessary for the synthesis
of purine and thymidine nucleotides and for the synthesis of methionine from homocysteine …
of purine and thymidine nucleotides and for the synthesis of methionine from homocysteine …
Vitamin D3 in fat tissue
M Blum, G Dolnikowski, E Seyoum, SS Harris… - Endocrine, 2008 - Springer
The literature describing vitamin D content of fat tissue is extremely limited. We conducted a
pilot study that measured the concentrations of vitamin D 3 in the fat tissue and serum of …
pilot study that measured the concentrations of vitamin D 3 in the fat tissue and serum of …
[HTML][HTML] Impact of DNA methylation on 3D genome structure
D Buitrago, M Labrador, JP Arcon, R Lema… - Nature …, 2021 - nature.com
Determining the effect of DNA methylation on chromatin structure and function in higher
organisms is challenging due to the extreme complexity of epigenetic regulation. We studied …
organisms is challenging due to the extreme complexity of epigenetic regulation. We studied …
Metabolic imbalance associated with methylation dysregulation and oxidative damage in children with autism
S Melnyk, GJ Fuchs, E Schulz, M Lopez… - Journal of autism and …, 2012 - Springer
Oxidative stress and abnormal DNA methylation have been implicated in the
pathophysiology of autism. We investigated the dynamics of an integrated metabolic …
pathophysiology of autism. We investigated the dynamics of an integrated metabolic …
Dietary and lifestyle factors of DNA methylation
Lifestyle factors, such as diet, smoking, physical activity, and body weight management, are
known to constitute the majority of cancer causes. Epigenetics has been widely proposed as …
known to constitute the majority of cancer causes. Epigenetics has been widely proposed as …
Potential local regulatory functions of inhibins, activins and follistatin in the ovary
PG Knight, C Glister - Reproduction, 2001 - rep.bioscientifica.com
The changing pattern of granulosa cell expression of inhibin/activin subunits and follistatin
during follicle development and their differential regulation by extrinsic and intraovarian …
during follicle development and their differential regulation by extrinsic and intraovarian …