Abstract Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) is presenting as a systemic disease associated with …

Intussusceptive angiogenesis is a dynamic intravascular process capable of dramatically
modifying the structure of the microcirculation. The distinctive structural feature of …

Blood travels throughout the body in an extensive network of vessels–arteries, veins and
capillaries. This vascular network is not static, but instead dynamically remodels in response …

VEGF induces normal or aberrant angiogenesis depending on its dose in the
microenvironment around each producing cell in vivo. This transition depends on the …

Angiogenesis, ie the development and growth of blood vessels, is a major topic of research
as it plays an important role in normal development and in various pathologies. Recent …

BACKGROUND & AIMS: Notch signaling mediates embryonic vascular development and
normal vascular remodeling; Notch1 knockout mice develop nodular regenerative …

The vasculature ensures optimal delivery of nutrients and oxygen throughout the body, and
to achieve this function it must continually adapt to varying tissue demands. Newly formed …

Intussusceptive angiogenesis (IA) is a complementary method to sprouting angiogenesis
(SA). The hallmark of IA is formation of trans-capillary tissue pillars, their fusion and …

Increasing experimental evidence suggests that IGF-1 may modulate tumor angiogenesis
via activation of the expression of VEGF in Ewing sarcomas and rhabdomyosarcomas. This …

Pathological angiogenesis contributes to cancer progression and chronic inflammatory
diseases. In inflammatory bowel disease, the microvasculature expands by intussusceptive …