[HTML][HTML] MicroRNA: A signature for cancer progression

BM Hussen, HJ Hidayat, A Salihi, DK Sabir… - Biomedicine & …, 2021 - Elsevier
MicroRNAs (miRNAs) are a group of small non-coding RNAs that post-transcriptionally
control expression of genes by targeting mRNAs. miRNA alterations partake in the …

MicroRNAs in development and disease

D Sayed, M Abdellatif - Physiological reviews, 2011 - journals.physiology.org
MicroRNAs (miRNAs) are a class of posttranscriptional regulators that have recently
introduced an additional level of intricacy to our understanding of gene regulation. There are …

Targeting microRNAs in cancer: rationale, strategies and challenges

R Garzon, G Marcucci, CM Croce - Nature reviews Drug discovery, 2010 - nature.com
MicroRNAs (miRNAs) are evolutionarily conserved small non-coding RNAs that regulate
gene expression. Early studies have shown that miRNA expression is deregulated in cancer …

microRNA regulation of inflammatory responses

RM O'Connell, DS Rao… - Annual review of …, 2012 - annualreviews.org
The mammalian inflammatory response is a rapid and complex physiological reaction to
noxious stimuli including microbial pathogens. Although inflammation plays a valuable role …

Physiological and pathological roles for microRNAs in the immune system

RM O'connell, DS Rao, AA Chaudhuri… - Nature Reviews …, 2010 - nature.com
Mammalian microRNAs (miRNAs) have recently been identified as important regulators of
gene expression, and they function by repressing specific target genes at the post …

MicroRNAs: the fine-tuners of Toll-like receptor signalling

LA O'neill, FJ Sheedy, CE McCoy - Nature reviews immunology, 2011 - nature.com
Toll-like receptor (TLR) signalling must be tightly regulated to avoid excessive inflammation
and to allow for tissue repair and the return to homeostasis after infection and tissue injury …

miR-146 and miR-155: two key modulators of immune response and tumor development

U Testa, E Pelosi, G Castelli, C Labbaye - Non-coding RNA, 2017 - mdpi.com
MicroRNAs (miRNAs or miRs) are a class of evolutionarily-conserved small, regulatory non-
coding RNAs, 19–3 nucleotides in length, that negatively regulate protein coding gene …

Nanoparticle-based therapy in an in vivo microRNA-155 (miR-155)-dependent mouse model of lymphoma

IA Babar, CJ Cheng, CJ Booth… - Proceedings of the …, 2012 - National Acad Sciences
MicroRNA-155 (miR-155) is an oncogenic microRNA that regulates several pathways
involved in cell division and immunoregulation. It is overexpressed in numerous cancers, is …

MicroRNA-155 Functions as an OncomiR in Breast Cancer by Targeting the Suppressor of Cytokine Signaling 1 Gene

S Jiang, HW Zhang, MH Lu, XH He, Y Li, H Gu, MF Liu… - Cancer research, 2010 - AACR
Abstract MicroRNA-155 (miR-155) is overexpressed in many human cancers; however, the
mechanisms by which miR-155 functions as a putative oncomiR are largely unknown. Here …

miR-155 in cancer drug resistance and as target for miRNA-based therapeutics

R Bayraktar, K Van Roosbroeck - Cancer and Metastasis Reviews, 2018 - Springer
Small non-coding microRNAs (miRNAs) are instrumental in physiological processes, such
as proliferation, cell cycle, apoptosis, and differentiation, processes which are often …