From hairballs to hypotheses–biological insights from microbial networks
L Röttjers, K Faust - FEMS microbiology reviews, 2018 - academic.oup.com
Microbial networks are an increasingly popular tool to investigate microbial community
structure, as they integrate multiple types of information and may represent systems-level …
structure, as they integrate multiple types of information and may represent systems-level …
Venn diagrams in bioinformatics
A Jia, L Xu, Y Wang - Briefings in bioinformatics, 2021 - academic.oup.com
Venn diagrams are widely used tools for graphical depiction of the unions, intersections and
distinctions among multiple datasets, and a large number of programs have been developed …
distinctions among multiple datasets, and a large number of programs have been developed …
Multi-omics single-cell data integration and regulatory inference with graph-linked embedding
ZJ Cao, G Gao - Nature Biotechnology, 2022 - nature.com
Despite the emergence of experimental methods for simultaneous measurement of multiple
omics modalities in single cells, most single-cell datasets include only one modality. A major …
omics modalities in single cells, most single-cell datasets include only one modality. A major …
Undulating changes in human plasma proteome profiles across the lifespan
Aging is a predominant risk factor for several chronic diseases that limit healthspan.
Mechanisms of aging are thus increasingly recognized as potential therapeutic targets …
Mechanisms of aging are thus increasingly recognized as potential therapeutic targets …
The transcriptional landscape of Arabidopsis thaliana pattern-triggered immunity
Plants tailor their metabolism to environmental conditions, in part through the recognition of
a wide array of self and non-self molecules. In particular, the perception of microbial or plant …
a wide array of self and non-self molecules. In particular, the perception of microbial or plant …
[HTML][HTML] In vivo antiviral host transcriptional response to SARS-CoV-2 by viral load, sex, and age
Despite limited genomic diversity, severe acute respiratory syndrome coronavirus 2 (SARS-
CoV-2) has shown a wide range of clinical manifestations in different patient populations …
CoV-2) has shown a wide range of clinical manifestations in different patient populations …
Multi-trait analysis for genome-wide association study of five psychiatric disorders
We conducted a cross-trait meta-analysis of genome-wide association study on
schizophrenia (SCZ)(n= 65,967), bipolar disorder (BD)(n= 41,653), autism spectrum …
schizophrenia (SCZ)(n= 65,967), bipolar disorder (BD)(n= 41,653), autism spectrum …
An atlas of cortical circular RNA expression in Alzheimer disease brains demonstrates clinical and pathological associations
Parietal cortex RNA-sequencing (RNA-seq) data were generated from individuals with and
without Alzheimer disease (AD; n control= 13; n AD= 83) from the Knight Alzheimer Disease …
without Alzheimer disease (AD; n control= 13; n AD= 83) from the Knight Alzheimer Disease …
Cell type-specific transcriptomics reveals that mutant huntingtin leads to mitochondrial RNA release and neuronal innate immune activation
The mechanisms by which mutant huntingtin (mHTT) leads to neuronal cell death in
Huntington's disease (HD) are not fully understood. To gain new molecular insights, we …
Huntington's disease (HD) are not fully understood. To gain new molecular insights, we …
Brain cell type specific gene expression and co-expression network architectures
Elucidating brain cell type specific gene expression patterns is critical towards a better
understanding of how cell-cell communications may influence brain functions and …
understanding of how cell-cell communications may influence brain functions and …