Association of insulin resistance and elevated androgen levels with polycystic ovarian syndrome (PCOS): a review of literature

Y Xu, J Qiao - Journal of healthcare engineering, 2022 - Wiley Online Library
The polycystic ovary syndrome (PCOS) is the disease featured by elevated levels of
androgens, ovulatory dysfunction, and morphological abnormalities. At reproductive stage of …

Deconstructing a syndrome: genomic insights into PCOS causal mechanisms and classification

M Dapas, A Dunaif - Endocrine reviews, 2022 - academic.oup.com
Polycystic ovary syndrome (PCOS) is among the most common disorders in women of
reproductive age, affecting up to 15% worldwide, depending on the diagnostic criteria …

Understanding the glucoregulatory mechanisms of metformin in type 2 diabetes mellitus

M Foretz, B Guigas, B Viollet - Nature Reviews Endocrinology, 2019 - nature.com
Despite its position as the first-line drug for treatment of type 2 diabetes mellitus, the
mechanisms underlying the plasma glucose level-lowering effects of metformin (1, 1 …

Long-term cardiometabolic disease risk in women with PCOS: a systematic review and meta-analysis

V Wekker, L Van Dammen, A Koning… - Human reproduction …, 2020 - academic.oup.com
BACKGROUND Polycystic ovary syndrome (PCOS) is associated with cardiometabolic
disease, but recent systematic reviews and meta-analyses of longitudinal studies that …

Metabolic syndrome—A new definition and management guidelines

P Dobrowolski, A Prejbisz, A Kuryłowicz… - Arterial …, 2022 - journals.viamedica.pl
The joint position paper by Polish Society of Hypertension, Polish Society for the Treatment
of Obesity, Polish Lipid Association, Polish Association for Study of Liver, Polish Society of …

Polycystic ovary syndrome: definition, aetiology, diagnosis and treatment

HF Escobar-Morreale - Nature Reviews Endocrinology, 2018 - nature.com
Polycystic ovary syndrome (PCOS) is one of the most common endocrine and metabolic
disorders in premenopausal women. Heterogeneous by nature, PCOS is defined by a …

[HTML][HTML] Polycystic ovary syndrome and cardiometabolic risk: Opportunities for cardiovascular disease prevention

O Osibogun, O Ogunmoroti, ED Michos - Trends in cardiovascular …, 2020 - Elsevier
Although polycystic ovary syndrome (PCOS) is one of the most common endocrine disorders
affecting women, its etiology is not entirely understood. Clinical symptoms of PCOS include …

[HTML][HTML] Criteria, prevalence, and phenotypes of polycystic ovary syndrome

D Lizneva, L Suturina, W Walker, S Brakta… - Fertility and sterility, 2016 - Elsevier
Polycystic ovary syndrome (PCOS) is a highly prevalent disorder effecting reproductive-
aged women worldwide. This article addresses the evolution of the criteria used to diagnosis …

[HTML][HTML] Polycystic ovary syndrome is transmitted via a transgenerational epigenetic process

NEH Mimouni, I Paiva, AL Barbotin, FE Timzoura… - Cell metabolism, 2021 - cell.com
Polycystic ovary syndrome (PCOS) is the most common reproductive and metabolic disorder
affecting women of reproductive age. PCOS has a strong heritable component, but its …

Progesterone actions and resistance in gynecological disorders

JA MacLean, K Hayashi - Cells, 2022 - mdpi.com
Estrogen and progesterone and their signaling mechanisms are tightly regulated to maintain
a normal menstrual cycle and to support a successful pregnancy. The imbalance of estrogen …