Insight into polyphenol and gut microbiota crosstalk: are their metabolites the key to understand protective effects against metabolic disorders?

M Koudoufio, Y Desjardins, F Feldman, S Spahis… - Antioxidants, 2020 - mdpi.com
Lifestyle factors, especially diet and nutrition, are currently regarded as essential avenues to
decrease modern-day cardiometabolic disorders (CMD), including obesity, metabolic …

Noncoding RNA as an influential epigenetic modulator with promising roles in cancer therapeutics

L Roy, O Chatterjee, D Bose, A Roy, S Chatterjee - Drug Discovery Today, 2023 - Elsevier
The epigenetic landscape has an important role in cellular homeostasis and its deregulation
leads to cancer. Noncoding (nc) RNA networks function as major regulators of cellular …

Epigenetic regulation in the pathogenesis of rheumatoid arthritis

C Yang, D Li, D Teng, Y Zhou, L Zhang… - Frontiers in …, 2022 - frontiersin.org
Rheumatoid arthritis (RA) is an autoimmune disease. The etiology of RA remains
undetermined and the pathogenesis is complex. There remains a paucity of ideal …

The impact of epigenetic modifications in myeloid malignancies

D Venney, A Mohd-Sarip, KI Mills - International Journal of Molecular …, 2021 - mdpi.com
Myeloid malignancy is a broad term encapsulating myeloproliferative neoplasms (MPN),
myelodysplastic syndrome (MDS) and acute myeloid leukaemia (AML). Initial studies into …

Long-term environmental metal exposure is associated with hypomethylation of CpG sites in NFKB1 and other genes related to oncogenesis

A Stepanyan, A Petrackova, S Hakobyan, J Savara… - Clinical …, 2023 - Springer
Background Long-term environmental exposure to metals leads to epigenetic changes and
may increase risks to human health. The relationship between the type and level of metal …

The Killer's Web: Interconnection between Inflammation, Epigenetics and Nutrition in Cancer

M Mecca, S Picerno, S Cortellino - International Journal of Molecular …, 2024 - mdpi.com
Inflammation is a key contributor to both the initiation and progression of tumors, and it can
be triggered by genetic instability within tumors, as well as by lifestyle and dietary factors …

Updates on the role of epigenetics in familial mediterranean fever (FMF)

A Chaaban, Z Salman, L Karam, PH Kobeissy… - Orphanet Journal of …, 2024 - Springer
Abstract Familial Mediterranean Fever (FMF) is an autosomal recessive autoinflammatory
disease caused by mutations in the MEFV (ME diterranean F e V er) gene that affects people …

Evolution, functions and dynamics of epigenetic mechanisms in animals

G Vogt - handbook of epigenetics, 2023 - Elsevier
DNA methylation, histone modifications, and non-coding RNAs are ubiquitous in the animal
kingdom. Histone modifications are apparently similar in all higher animal taxa but DNA …

[HTML][HTML] Epigenetic mechanisms in vascular inflammation: modulation of endothelial adhesion molecules and endothelium-leukocyte adhesion

N Calabriso, M Massaro, E Scoditti… - Frontiers in Bioscience …, 2023 - imrpress.com
The endothelium, an essential component of the vascular system, plays a critical role in the
inflammatory response. Under pro-inflammatory stimuli, endothelial cells undergo activation …

Alterations in growth habit to channel end-of-season perennial reserves towards increased yield and reduced regrowth after defoliation in upland cotton (Gossypium …

S Naveed, N Gandhi, G Billings, Z Jones… - International Journal of …, 2023 - mdpi.com
Cotton (Gossypium spp.) is the primary source of natural textile fiber in the US and a major
crop in the Southeastern US Despite constant efforts to increase the cotton fiber yield, the …