The lactate and the lactate dehydrogenase in inflammatory diseases and major risk factors in COVID-19 patients
GS Gupta - Inflammation, 2022 - Springer
Lactate dehydrogenase (LDH) is a terminating enzyme in the metabolic pathway of
anaerobic glycolysis with end product of lactate from glucose. The lactate formation is crucial …
anaerobic glycolysis with end product of lactate from glucose. The lactate formation is crucial …
Understanding long COVID; mitochondrial health and adaptation—old pathways, new problems
Many people infected with the SARS-CoV-2 suffer long-term symptoms, such as “brain fog”,
fatigue and clotting problems. Explanations for “long COVID” include immune imbalance …
fatigue and clotting problems. Explanations for “long COVID” include immune imbalance …
Insulin resistance in peripheral tissues and the brain: a tale of two sites
The concept of insulin resistance has been around since a few decades after the discovery
of insulin itself. To allude to the classic Charles Dicken's novel published 62 years before the …
of insulin itself. To allude to the classic Charles Dicken's novel published 62 years before the …
[HTML][HTML] Interplay between comorbidities and long COVID: challenges and multidisciplinary approaches
Long COVID, a name often given to the persistent symptoms following acute SARS-CoV-2
infection, poses a multifaceted challenge for health. This review explores the intrinsic …
infection, poses a multifaceted challenge for health. This review explores the intrinsic …
Blood-brain barrier penetration of non-replicating SARS-CoV-2 and S1 variants of concern induce neuroinflammation which is accentuated in a mouse model of …
MA Erickson, AF Logsdon, EM Rhea… - Brain, behavior, and …, 2023 - Elsevier
COVID-19 and especially Long COVID are associated with severe CNS symptoms and may
place persons at risk to develop long-term cognitive impairments. Here, we show that two …
place persons at risk to develop long-term cognitive impairments. Here, we show that two …
Endocrine follow-up during post-acute COVID-19: practical recommendations based on available clinical evidence
Objective COVID-19 affects multiple endocrine organ systems during the disease course.
However, follow-up data post-COVID-19 is scarce; hitherto available limited data suggest …
However, follow-up data post-COVID-19 is scarce; hitherto available limited data suggest …
[HTML][HTML] Psychotropic drug repurposing for COVID-19: a systematic review and meta-analysis
Several psychotropic drugs, including antidepressants (AD), mood stabilizers, and
antipsychotics (AP) have been suggested to have favorable effects in the treatment of …
antipsychotics (AP) have been suggested to have favorable effects in the treatment of …
Sodium–glucose co-transporter-2 inhibitors for hospitalised patients with COVID-19: a prospective meta-analysis of randomised trials
C Vale, PJ Godolphin, D Fisher, PW Horby… - The Lancet Diabetes & …, 2024 - thelancet.com
Background Sodium–glucose co-transporter-2 (SGLT2) inhibitors have been proposed as a
potential treatment for adults hospitalised with COVID-19, due to their potential anti …
potential treatment for adults hospitalised with COVID-19, due to their potential anti …
Acute respiratory distress syndrome
KD Wick, LB Ware, MA Matthay - bmj, 2024 - bmj.com
The understanding of acute respiratory distress syndrome (ARDS) has evolved greatly since
it was first described in a 1967 case series, with several subsequent updates to the definition …
it was first described in a 1967 case series, with several subsequent updates to the definition …
Combining L-Arginine with vitamin C improves long-COVID symptoms: The LINCOLN Survey
Introduction Recent evidence suggests that oxidative stress and endothelial dysfunction play
critical roles in the pathophysiology of COVID-19 and Long-COVID. We hypothesized that a …
critical roles in the pathophysiology of COVID-19 and Long-COVID. We hypothesized that a …