Histamine modulates several aspects of energy homeostasis. By activating histamine
receptors in the hypothalamus the bioamine influences thermoregulation, its circadian …

Background Substantial evidence has demonstrated that maternal high-fat (HF)
consumption during gestation and lactation plays as a risk factor for neurodevelopmental …

The human intestine hosts a vast and complex microbial community that is vital for
maintaining several functions related with host health. The processes that determine the gut …

Objectives A high histamine H1 receptor (H1R) expression cell membrane chromatography
(CMC) method was developed to investigate the affinity of ligands for H1R. Methods The …

Prenatal nutrient exposures can impact on brain development and disease susceptibility
across the lifespan. It is well established that maternal macronutrient intake during …

Neurotensin is an endogenous neuropeptide that acts as a potent modulator of ventral
tegmental area (VTA) neurotransmission. The present study was aimed at determining VTA …

Bipolar disorder (BD) is an extremely disabling psychiatric disease, characterized by
alternate states of mania (or hypomania) and depression with euthymic states in between …

Bu çalışmada, diyet indüklü obezite ve egzersiz ile beyinde enerji metabolizması ile
doğrudan veya dolaylı olarak ilgisi olduğu kabul edilen nörotransmitterler ve nöropeptitler ve …

Ketotifen (K) is a first-generation antihistamine with antiinflammatory potency. It penetrates
the blood-brain barrier (BBB) and causes a sedative side effect. Norketotifen (N) is an active …