[HTML][HTML] Unlocking the microbial studies through computational approaches: how far have we reached?
The metagenomics approach accelerated the study of genetic information from uncultured
microbes and complex microbial communities. In silico research also facilitated an …
microbes and complex microbial communities. In silico research also facilitated an …
[PDF][PDF] Safety by design: Biosafety and biosecurity in the age of synthetic genomics
Technologies to profoundly engineer biology are becoming increasingly affordable,
powerful, and accessible to a widening group of actors. While offering tremendous potential …
powerful, and accessible to a widening group of actors. While offering tremendous potential …
[HTML][HTML] Plastic leachate exposure drives antibiotic resistance and virulence in marine bacterial communities
Plastic pollution is a serious global problem, with more than 12 million tonnes of plastic
waste entering the oceans every year. Plastic debris can have considerable impacts on …
waste entering the oceans every year. Plastic debris can have considerable impacts on …
[HTML][HTML] Improved understanding of biorisk for research involving microbial modification using annotated sequences of concern
Regulation of research on microbes that cause disease in humans has historically been
focused on taxonomic lists of 'bad bugs'. However, given our increased knowledge of these …
focused on taxonomic lists of 'bad bugs'. However, given our increased knowledge of these …
[HTML][HTML] Beyond Biosecurity by Taxonomic Lists: Lessons, Challenges, and Opportunities
P Millett, T Alexanian, KR Brink, SR Carter… - Health …, 2023 - liebertpub.com
Taxonomic lists—that is, lists that give a set of species (eg, Yersinia pestis) or broader
taxonomic groups (eg, SARS-related coronavirus) to be regulated—are a common tool used …
taxonomic groups (eg, SARS-related coronavirus) to be regulated—are a common tool used …
Deep learning-based real-time detection of novel pathogens during sequencing
JM Bartoszewicz, U Genske… - Briefings in …, 2021 - academic.oup.com
Novel pathogens evolve quickly and may emerge rapidly, causing dangerous outbreaks or
even global pandemics. Next-generation sequencing is the state of the art in open-view …
even global pandemics. Next-generation sequencing is the state of the art in open-view …
[HTML][HTML] KOMB: K-core based de novo characterization of copy number variation in microbiomes
Characterizing metagenomes via kmer-based, database-dependent taxonomic classification
has yielded key insights into underlying microbiome dynamics. However, novel approaches …
has yielded key insights into underlying microbiome dynamics. However, novel approaches …
Exploring the role of mobile genetic elements in shaping plant–bacterial interactions for sustainable agriculture and ecosystem health
Societal Impact Statement Plants and bacteria interact in complex ways that are crucial to
the health and productivity of native vegetation and croplands. While the range of …
the health and productivity of native vegetation and croplands. While the range of …
[HTML][HTML] Analysis of bronchoalveolar lavage fluid metatranscriptomes among patients with COVID-19 disease
To better understand the potential relationship between COVID-19 disease and
hologenome microbial community dynamics and functional profiles, we conducted a …
hologenome microbial community dynamics and functional profiles, we conducted a …
Leveraging Large Language Models for Predicting Microbial Virulence from Protein Structure and Sequence
In the aftermath of COVID-19, screening for pathogens has never been a more relevant
problem. However, computational screening for pathogens is challenging due to a variety of …
problem. However, computational screening for pathogens is challenging due to a variety of …