An update is available for this article. Description: The purpose of this guideline from the
American College of Physicians (ACP) is to present updated clinical recommendations on …

Objectives The purpose of this systematic review of randomized controlled trials (RCTs) was
to evaluate the effectiveness, safety, and tolerability of psilocybin in adult patients with major …

Background Various effective treatments for depression exist. We aimed to identify the most
effective first-line treatments for new episodes of less and more severe depression (defined …

Abstract Introduction The Major Depressive Disorder (MDD) is a mental health disorder that
affects millions of people worldwide. It is characterized by persistent feelings of sadness …

In anxiety, depression and psychosis, there has been frustratingly slow progress in
developing novel therapies that make a substantial difference in practice, as well as in …

Depressive disorders are heterogeneous in nature, and their global reach makes them the
cause of suffering for a million individuals worldwide. Standard treatment does not work for …

Importance Approximately 9% of US adults experience major depression each year, with a
lifetime prevalence of approximately 17% for men and 30% for women. Observations Major …

Background Utilisation of health services is low and delayed among individuals with mood
mental disorders and anxiety disorders, despite high disease burdens and available …

Background Depression, a prevalent mental disorder, has shown an increasing trend in
recent years, imposing a significant burden on health and society. Adequate sleep has been …

The surveillance search since the inaugural review was published covers the search
periods from 8 August 2022 to 22 August 2023. To inform the surveillance search, we …