Cholestatic and non-alcoholic fatty liver disease (NAFLD) share several key
pathophysiological mechanisms which can be targeted by novel therapeutic concepts that …

Background: Fourteen clinical trials have not shown a consistent benefit of combination
therapy with levothyroxine (LT4) and liothyronine (LT3). Despite the publication of these …

Background: Thyroid hormones (THs) exert a strong influence on mammalian lipid
metabolism at the systemic and hepatic levels by virtue of their roles in regulating circulating …

Thyroid hormone (TH) plays a critical role in maintaining metabolic homeostasis throughout
life. It is well known that the liver and thyroid are intimately linked, with TH playing important …

Nonalcoholic fatty liver disease (NAFLD) is a worldwide rising challenge because of hepatic,
but also extrahepatic, complications. Thyroid hormones are master regulators of energy and …

Nonalcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver disease
worldwide and its incidence is definitely increasing. NAFLD is a metabolic disease with …

Non-alcoholic fatty liver disease (NAFLD) encompasses a spectrum of fatty liver disease,
including non-alcoholic fatty liver (NAFL) and its more progressive form, non-alcoholic …

While the links between metabolic dysfunction associated steatotic liver disease liver
disease (MASLD) and obesity, insulin resistance are widely appreciated, there are a host of …

Thyroid hormones control lipid metabolism by exhibiting specific effects on the liver and
adipose tissue in a coordinated manner. Different diseases of the thyroid gland can result in …

Background: It is currently uncertain whether primary hypothyroidism is associated with
nonalcoholic fatty liver disease (NAFLD). We performed a meta-analysis of relevant studies …