[HTML][HTML] Epithelial-mesenchymal transition in cancer: a historical overview
D Ribatti, R Tamma, T Annese - Translational oncology, 2020 - Elsevier
Abstract Epithelial-mesenchymal transitions (EMTs), the acquisition of mesenchymal
features from epithelial cells, occur during some biological processes and are classified into …
features from epithelial cells, occur during some biological processes and are classified into …
Molecular mechanisms of epithelial–mesenchymal transition
S Lamouille, J Xu, R Derynck - Nature reviews Molecular cell biology, 2014 - nature.com
The transdifferentiation of epithelial cells into motile mesenchymal cells, a process known as
epithelial–mesenchymal transition (EMT), is integral in development, wound healing and …
epithelial–mesenchymal transition (EMT), is integral in development, wound healing and …
[HTML][HTML] Epithelial-mesenchymal transitions in development and disease
The epithelial to mesenchymal transition (EMT) plays crucial roles in the formation of the
body plan and in the differentiation of multiple tissues and organs. EMT also contributes to …
body plan and in the differentiation of multiple tissues and organs. EMT also contributes to …
Snail, Zeb and bHLH factors in tumour progression: an alliance against the epithelial phenotype?
The molecular mechanisms that underlie tumour progression are still poorly understood, but
recently our knowledge of particular aspects of some of these processes has increased …
recently our knowledge of particular aspects of some of these processes has increased …
[HTML][HTML] Cancer metastasis is accelerated through immunosuppression during Snail-induced EMT of cancer cells
C Kudo-Saito, H Shirako, T Takeuchi, Y Kawakami - Cancer cell, 2009 - cell.com
Epithelial-mesenchymal transition (EMT) is a key step toward cancer metastasis, and Snail
is a major transcription factor governing EMT. Here, we demonstrate that Snail-induced EMT …
is a major transcription factor governing EMT. Here, we demonstrate that Snail-induced EMT …
Preparing the “soil”: the premetastatic niche
Current focus on cancer metastasis has centered on the intrinsic factors regulating the cell
autonomous homing of the tumor cells to the metastatic site. Specific up-regulation of …
autonomous homing of the tumor cells to the metastatic site. Specific up-regulation of …
[HTML][HTML] Heterogeneity in circulating tumor cells: the relevance of the stem-cell subset
C Agnoletto, F Corrà, L Minotti, F Baldassari, F Crudele… - Cancers, 2019 - mdpi.com
The release of circulating tumor cells (CTCs) into vasculature is an early event in the
metastatic process. The analysis of CTCs in patients has recently received widespread …
metastatic process. The analysis of CTCs in patients has recently received widespread …
[HTML][HTML] ERβ impedes prostate cancer EMT by destabilizing HIF-1α and inhibiting VEGF-mediated snail nuclear localization: implications for Gleason grading
P Mak, I Leav, B Pursell, D Bae, X Yang, CA Taglienti… - Cancer cell, 2010 - cell.com
High Gleason grade prostate carcinomas are aggressive, poorly differentiated tumors that
exhibit diminished estrogen receptor β (ERβ) expression. We report that a key function of …
exhibit diminished estrogen receptor β (ERβ) expression. We report that a key function of …
Chemoresistance to paclitaxel induces epithelial-mesenchymal transition and enhances metastatic potential for epithelial ovarian carcinoma cells
H Kajiyama, K Shibata, M Terauchi… - International …, 2007 - spandidos-publications.com
The aim of this study was to assess paclitaxel resistant-epithelial ovarian carcinoma (EOC)
cells for cellular morphology, motility, and molecular changes consistent with epithelial …
cells for cellular morphology, motility, and molecular changes consistent with epithelial …
MicroRNAs and the hallmarks of cancer
T Dalmay, DR Edwards - Oncogene, 2006 - nature.com
It has become clear that particular microRNAs (miRNAs) function either as tumour
suppressors or oncogenes, whose loss or overexpression, respectively, has diagnostic and …
suppressors or oncogenes, whose loss or overexpression, respectively, has diagnostic and …