Cancer represents one of the most pernicious public health problems with a high mortality
rate among patients worldwide. Chemotherapy is one of the major therapeutic approaches …

Chemotherapeutic agents may adversely affect the nervous system, including the neural
precursor cells as well as the white matter. Although the mechanisms are not completely …

Cisplatin, an inorganic complex of platinum, is a chemotherapeutic drug that has been used
for 45 years. Despite the progress of pharmaceutical sciences and medicine and the …

Cisplatin is a widely used chemotherapeutic agent in treating various types of cancers.
However, it can induce neurotoxicity and nephrotoxicity, limiting its dose and clinical use …

Cisplatin, a small platinum-containing molecule, is a widely used, highly effective anticancer
drug. However, severe side effects have been found in cancer patients treated with cisplatin …

Cisplatin is a chemotherapeutic agent used in the treatment of malignant tumors. A major
clinical limitation of cisplatin is its potential toxic effects, including neurotoxicity. Edaravone …

Peripheral neurotoxicity is a frequent dose‐limiting side effect of the chemotherapeutic agent
cisplatin. This study was conducted to investigate the preventive effect of oxytocin (OT) on …

The present study has been designed to investigate the role of curcumin on cisplatin-
inducedcognitive impairment and to reveal mechanisms of cisplatin's detrimental actions on …

Background: Neuropathic pain is a common side-effect of chemotherapy. Although precise
mechanisms are unclear, oxidative stress and mitochondrial damage are involved. We …

Introduction: Cisplatin is a highly effective antineoplastic drug with an extremely current
mechanism of action. Cisplatin-induced side effects are dose-dependent and limit the …