Reductions play a key role in organic synthesis, producing chiral products with new
functionalities. Enzymes can catalyse such reactions with exquisite stereo‐, regio‐and …

When challenged by a difficult reduction reaction, a chemist should always also consider
biocatalysis in synthesis planning. The inherent selectivity of enzymes has been known for …

This review updates the principal methods used to obtain dynamic kinetic resolution (DKR)
by either enzymatic or nonenzymatic methods, covering the literature from 2008 to the …

Alcohol dehydrogenases (ADHs) have become important catalysts for stereoselective
oxidation and reduction reactions of alcohols, aldehydes and ketones. The aim of this …

New methods continue to be developed for the dynamic kinetic resolution (DKR) and
deracemisation of racemic chiral compounds, in particular alcohols, amines and amino …

The ability to site-selectively modify equivalent functional groups in a molecule has the
potential to streamline syntheses and increase product yields by lowering step counts …

Microbial enzymes and cells continue to be important tools and nature's privileged chiral
catalysts for performing asymmetric biocatalysis from the analytical small scale to the …

Biocatalyzed asymmetric reduction of ketones is an environmentally friendly approach and
one of the most cost-effective routes for producing chiral alcohols. In comparison with the …

Sažetak The alcohol dehydrogenase from Lactobacillus brevis (LbADH) is a versatile
catalyst for enantioselective reduction of ketones. Its substrate scope is wide with high regio …

Over the past two decades, the domains of both frontline synthetic organic chemistry and
process chemistry have seen an increase in crosstalk between asymmetric organic …