Genetic code expansion is a promising genetic engineering technology that incorporates
noncanonical amino acids into proteins alongside the natural set of 20 amino acids. This …

Expanding the chemical repertoire of natural and artificial protein-based polymers (PBPs)
can enable the production of sequence-defined, yet chemically diverse, biopolymers with …

The 11 lytic transglycosylases of Pseudomonas aeruginosa have overlapping activities in
the turnover of the cell‐wall peptidoglycan. Rare lipoprotein A (RlpA) is distinct among the …

The mechanism, regioselectivity, chemoselectivity, and the effects of substituents were
explored using density functional theory (DFT) in the oxidative functionalization of …

Across scales, many biological phenomena, such as protein folding or bioadhesion and
cohesion, rely on synergistic effects of different amino acid side chains at multiple positions …

The rational design of light-responsive proteins and protein-based polymers requires both a
photoswitch with suitable light-responsive properties and the ability to incorporate it at …

Peptidoglycan is a major constituent of the bacterial cell wall. Its integrity as a polymeric
edifice is critical for bacterial survival and, as such, it is a preeminent target for antibiotics …

RNA‐based tools for biological and pharmacological research are raising an increasing
interest. Among these, RNA aptamers whose biological activity can be controlled via …

Cell-free unnatural protein synthesis (CFUPS) system, as a powerful unnatural protein
synthesis platform, has been successfully developed from a small-batch laboratory scale to …

Inspired by nature, scientists have harnessed the natural protein translation machinery to
produce intricate and precise protein‐based polymers (PBPs)—composed of natural amino …