The EGFR signalling system in the liver: from hepatoprotection to hepatocarcinogenesis
C Berasain, MA Avila - Journal of gastroenterology, 2014 - Springer
The liver displays an outstanding wound healing and regenerative capacity unmatched by
any other organ. This reparative response is governed by a complex network of …
any other organ. This reparative response is governed by a complex network of …
Cancer exosomes induce tumor innervation
Patients with densely innervated tumors suffer with increased metastasis and decreased
survival as compared to those with less innervated tumors. We hypothesize that in some …
survival as compared to those with less innervated tumors. We hypothesize that in some …
Dual role of the PTPN13 tyrosine phosphatase in cancer
In this review article, we present the current knowledge on PTPN13, a class I non-receptor
protein tyrosine phosphatase identified in 1994. We focus particularly on its role in cancer …
protein tyrosine phosphatase identified in 1994. We focus particularly on its role in cancer …
[HTML][HTML] Metastatic model of HPV+ oropharyngeal squamous cell carcinoma demonstrates heterogeneity in tumor metastasis
DW Vermeer, JD Coppock, E Zeng, KM Lee… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Human papillomavirus induced (HPV+) cancer incidence is rapidly rising, comprising 60–
80% of oropharyngeal squamous cell carcinomas (OPSCCs); while rare …
80% of oropharyngeal squamous cell carcinomas (OPSCCs); while rare …
MUC1 triggers lineage plasticity of Her2 positive mammary tumors
Z Pang, X Dong, H Deng, C Wang, X Liao, C Liao… - Oncogene, 2022 - nature.com
Aberrant overexpression of mucin 1 (MUC1) and human epidermal growth factor receptor 2
(HER2) are often observed in breast cancer. However, the role of concomitant MUC1/HER2 …
(HER2) are often observed in breast cancer. However, the role of concomitant MUC1/HER2 …
[HTML][HTML] Co-treatment with panitumumab and trastuzumab augments response to the MEK inhibitor trametinib in a patient-derived xenograft model of pancreatic …
JM Lindberg, TE Newhook, SJ Adair, DM Walters… - Neoplasia, 2014 - Elsevier
Kirsten rat sarcoma viral oncogene homolog (KRAS) mutations and epidermal growth factor
receptor (EGFR) family signaling are drivers of tumorigenesis in pancreatic ductal …
receptor (EGFR) family signaling are drivers of tumorigenesis in pancreatic ductal …
[HTML][HTML] Predictive biomarkers for response to TGF-β inhibition in resensitizing chemo (radiated) esophageal adenocarcinoma
Epithelial-mesenchymal transition (EMT) has been identified as a driver of therapy
resistance, particularly in esophageal adenocarcinoma (EAC), where transforming growth …
resistance, particularly in esophageal adenocarcinoma (EAC), where transforming growth …
EFNB1 acts as a novel prognosis marker in glioblastoma through bioinformatics methods and experimental validation
Y Shi, Y Sun, H Cheng, C Wang - Journal of oncology, 2021 - Wiley Online Library
Purpose. Ephrin B1 (EFNB1), the Eph‐associated receptor tyrosine kinase ligand, is
suggested to have an important function in neurodevelopment. However, its contribution to …
suggested to have an important function in neurodevelopment. However, its contribution to …
CSCdb: a cancer stem cells portal for markers, related genes and functional information
Cancer stem cells (CSCs), which have the ability to self-renew and differentiate into various
tumor cell types, are a special class of tumor cells. Characterizing the genes involved in …
tumor cell types, are a special class of tumor cells. Characterizing the genes involved in …
[HTML][HTML] Initiation of esophageal squamous cell carcinoma (ESCC) in a murine 4-nitroquinoline-1-oxide and alcohol carcinogenesis model
K Osei-Sarfo, AM Urvalek, XH Tang, T Scognamiglio… - Oncotarget, 2015 - ncbi.nlm.nih.gov
Esophageal squamous cell carcinomas (ESCCs) are very common, aggressive tumors, and
are often associated with alcohol and tobacco abuse. Because ESCCs exhibit high …
are often associated with alcohol and tobacco abuse. Because ESCCs exhibit high …