To bridge the gap between organ demand and supply, xenotransplantation has long been
considered as a realistic option for end-stage organ failure. Early this year this promise …

Progress in pig organ xenotransplantation has been made largely through (1) genetic
engineering of the organ-source pig to protect its tissues from the human innate immune …

Genetically engineered (GE) pigs with various combinations of genetic profiles have been
developed using heterologous promoters. This study aimed to identify autologous promoters …

Optimization is required for these therapies to be best utilized in xenotransplantation as
differences exist between allo-and xenotransplantation including its combination with other …

Previously, we reported that tissue factor (Tf) was included in the list of differentially
expressed genes as an upregulated gene in a rejected porcine heart after …

Brassica napus (rapeseed) suffers from waterlogging, leading to yield loss. ERF-Ⅶ
transcription factors are proved to be key components of oxygen sensing response in plants …

Gelenkverletzungen bzw. Verletzungen des Knorpels können langfristig durch auftretende
inflammatorische und degradative Prozesse in einer post-traumatischen Arthrose …

Neuromuscular diseases are a broad group of debilitating disorders that impair muscle
functioning. Duchenne muscular dystrophy (DMD) is the most common hereditary form of …

The use of genetically modified pigs as xeno-donors is a promising option to overcome the
shortage of donor organs. This work describes the development of the" Smart Graft" …