Heart failure (HF) is an acute or chronic clinical syndrome that results in a decrease in
cardiac output and an increase in intracardiac pressure at rest or upon exertion. The …

Abstract Runt-related transcription factor-1 (RUNX1), also known as acute myeloid
leukaemia 1 protein (AML1), is a member of the core-binding factor family of transcription …

Since the new severe acute respiratory syndrome coronavirus 2 (SARS-CoV2) has emerged
from China, the infection (novel corona virus disease-2019, COVID-19) has affected many …

The use of sodium-glucose co-transporter 2 inhibitors to treat heart failure with preserved
ejection fraction (HFpEF) is under investigation in ongoing clinical trials, but the exact …

Aim: Angiotensin Ⅱ (Ang Ⅱ) produces reactive oxygen species (ROS), thus contributing to
the development of cardiac hypertrophy and subsequent heart failure, and stimulates the …

Cardiomyocytes can adapt their size, shape, and orientation in response to altered
biomechanical or biochemical stimuli. The process by which the heart undergoes structural …

Subjects conceived through assisted reproductive technologies (ART) potentially suffer from
impaired left ventricular (LV) function due to premature vascular aging. This study aimed to …

Hypertension (HTN) is the single greatest risk factor for potentially fatal cardiovascular
diseases. One cause of HTN is inappropriately increased sympathetic nervous system …

Background Activation of glucagon-like peptide-1 (GLP-1) receptors improves insulin
sensitivity and induces vasodilatation and diuresis. AC3174 is a peptide analogue with …

Abstract Study Objective This study aimed to determine if variants in NR3C2, which codes
the target protein of spironolactone, or CYP11B2, which is involved in aldosterone synthesis …