Gut microbiota and cancer: from pathogenesis to therapy

S Vivarelli, R Salemi, S Candido, L Falzone… - Cancers, 2019 - mdpi.com
Cancer is a multifactorial pathology and it represents the second leading cause of death
worldwide. In the recent years, numerous studies highlighted the dual role of the gut …

Campylobacter jejuni: collective components promoting a successful enteric lifestyle

PM Burnham, DR Hendrixson - Nature Reviews Microbiology, 2018 - nature.com
Campylobacter jejuni is the leading cause of bacterial diarrhoeal disease in many areas of
the world. The high incidence of sporadic cases of disease in humans is largely due to its …

Campylobacter jejuni promotes colorectal tumorigenesis through the action of cytolethal distending toxin

Z He, RZ Gharaibeh, RC Newsome, JL Pope… - Gut, 2019 - gut.bmj.com
Objective Campylobacter jejuni produces a genotoxin, cytolethal distending toxin (CDT),
which has DNAse activity and causes DNA double-strand breaks. Although C. jejuni …

Immunogenicity of induced pluripotent stem cells

T Zhao, ZN Zhang, Z Rong, Y Xu - Nature, 2011 - nature.com
Induced pluripotent stem cells (iPSCs), reprogrammed from somatic cells with defined
factors, hold great promise for regenerative medicine as the renewable source of autologous …

Escherichia coli induces DNA damage in vivo and triggers genomic instability in mammalian cells

G Cuevas-Ramos, CR Petit, I Marcq… - Proceedings of the …, 2010 - National Acad Sciences
Escherichia coli is a normal inhabitant of the human gut. However, E. coli strains of
phylogenetic group B2 harbor a genomic island called “pks” that codes for the production of …

[HTML][HTML] Discovery and validation of potential bacterial biomarkers for lung cancer

X Yan, M Yang, J Liu, R Gao, J Hu, J Li… - American journal of …, 2015 - ncbi.nlm.nih.gov
Microbes are residents in a number of body sites, including the oral and nasal cavities,
which are connected to the lung via the pharynx. The associations between oral diseases …

[HTML][HTML] Mucins in the mucosal barrier to infection

SK Linden, P Sutton, NG Karlsson, V Korolik… - Mucosal …, 2008 - Elsevier
The mucosal tissues of the gastrointestinal, respiratory, reproductive, and urinary tracts, and
the surface of the eye present an enormous surface area to the exterior environment. All of …

Escherichia coli Induces DNA Double-Strand Breaks in Eukaryotic Cells

JP Nougayrède, S Homburg, F Taieb, M Boury… - Science, 2006 - science.org
Transient infection of eukaryotic cells with commensal and extraintestinal pathogenic
Escherichia coli of phylogenetic group B2 blocks mitosis and induces megalocytosis. This …

Facultative symbionts in aphids and the horizontal transfer of ecologically important traits

KM Oliver, PH Degnan, GR Burke… - Annual review of …, 2010 - annualreviews.org
Aphids engage in symbiotic associations with a diverse assemblage of heritable bacteria. In
addition to their obligate nutrient-provisioning symbiont, Buchnera aphidicola, aphids may …

Molecular mechanisms of postbiotics in colorectal cancer prevention and treatment

AH Rad, L Aghebati-Maleki, HS Kafil… - Critical reviews in food …, 2021 - Taylor & Francis
The occurrence of colorectal cancer (CRC) has been rising expeditiously and anticipated
that 2.4 million new occasions of CRC will be detected yearly around the world until the year …