Biomolecular condensates are micron-scale compartments in eukaryotic cells that lack
surrounding membranes but function to concentrate proteins and nucleic acids. These …

Liquid–liquid phase separation (LLPS) is now recognized as a common mechanism
underlying regulation of enzyme activity in cells. Insights from studies in cells are …

Biochemical processes inside the cell take place in a complex environment that is highly
crowded, heterogeneous, and replete with interfaces. The recently recognized importance of …

Living cells have evolved over billions of years to develop structural and functional
complexity with numerous intracellular compartments that are formed due to liquid–liquid …

Coacervate microdroplets produced by liquid–liquid phase separation have been used as
synthetic protocells that mimic the dynamical organization of membrane‐free organelles in …

Liquid–liquid phase separation (LLPS) in biology is a recently appreciated means of
intracellular compartmentalization. Because the mechanisms driving phase separations are …

Protein encapsulation is a growing area of interest, particularly in the fields of food science
and medicine. The sequestration of protein cargoes is achieved using a variety of methods …

Living cells have long been a source of inspiration for chemists. Their capacity of performing
complex tasks relies on the spatiotemporal coordination of matter and energy fluxes. Recent …

This Perspective focuses on RNA in biological and nonbiological compartments resulting
from liquid–liquid phase separation (LLPS), with an emphasis on origins of life. In extant …

Liquid–liquid phase separation has drawn attention as many neurodegeneration or cancer-
associated proteins are able to form liquid membraneless compartments (condensates) by …