Recent efforts to construct reference maps of cellular phenotypes have expanded the
volume and diversity of single-cell omics data, providing an unprecedented resource for …

Single-cell transcriptomics has broadened our understanding of cellular diversity and gene
expression dynamics in healthy and diseased tissues. Recently, spatial transcriptomics has …

Transformer‐based foundation models such as ChatGPTs have revolutionized our daily life
and affected many fields including bioinformatics. In this perspective, we first discuss about …

The great capability of AI large language models (LLMs) pre-trained on massive natural
language data has inspired scientists to develop a few …

Spatial proteomics can visualize and quantify protein expression profiles within tissues at
single-cell resolution. Although spatial proteomics can only detect a limited number of …

Transfer learning has revolutionized fields including natural language understanding and
computer vision by leveraging large‐scale general datasets to pretrain models with …

Recent development of large language models (LLMs) in AI has inspired scientists to
develop a few large-scale AI foundation models for single-cell transcriptomics or large …

Abstract Chronic Kidney Disease (CKD) and its subset Diabetic Kidney Disease (DKD) are
progressive conditions that affect more than 850 million people worldwide. Diabetes …

Atherosclerosis, a major cause of cardiovascular diseases, is characterized by the buildup of
lipids and chronic inflammation in the arteries, leading to plaque formation and potential …