The central nervous system is generated from progenitor cells that are recognized as neural
stem cells (NSCs). NSCs are defined as undifferentiated neural cells that are characterized …

Spinal cord injury (SCI) in mammals results in functional deficits that are mostly permanent
due in part to the inability of severed axons to regenerate. Several types of growth-inhibitory …

This study delves deeper into the impact of environmental temperature variations on the
nervous system in teleost fish. Previous research has demonstrated that exposing adult …

NEU1 sialidase hydrolyzes sialic acids from glycoconjugates in lysosomes. Deficiency of
NEU1 causes sialidosis with symptoms including facial dysmorphism, bone dysplasia, and …

Gangliosides are sialylated glycosphingolipids (GSLs) with essential but enigmatic functions
in brain activities and neural stem cell (NSC) maintenance. Our group has pioneered …

Gangliosides play an imperative role in cell signaling, neuronal recovery, apoptosis, and
other physiological processes. For example, GM3 can regulate hypothalamic leptin …

This study aimed to determine the expression and distribution of gangliosides in specific
regions of the brains of rainbow trout (Oncorhynchus mykiss Walbaum) and common carp …

In this preliminary investigation, a low-grade astrocytoma (AcT) is investigated by high-
resolution (HR) mass spectrometry (MS) aiming at characterization of gangliosides with …

Lysosomal storage diseases are the most common cause of neurodegeneration in children.
They are characterised at the cellular level by the accumulation of storage material within …

The central nervous system (CNS) harbors multiple glial fibrillary acidic protein (GFAP)
expressing cell types. In addition to the most abundant cell type of the CNS, the astrocytes …